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Diverse Brain Myeloid Expression Profiles Reveal Distinct Microglial Activation States and Aspects of Alzheimer's Disease Not Evident in Mouse Models.
Friedman BA, Srinivasan K, Ayalon G, Meilandt WJ, Lin H, Huntley MA, Cao Y, Lee SH, Haddick PCG, Ngu H, Modrusan Z, Larson JL, Kaminker JS, van der Brug MP, Hansen DV. Friedman BA, et al. Among authors: larson jl. Cell Rep. 2018 Jan 16;22(3):832-847. doi: 10.1016/j.celrep.2017.12.066. Cell Rep. 2018. PMID: 29346778 Free article.
Untangling the brain's neuroinflammatory and neurodegenerative transcriptional responses.
Srinivasan K, Friedman BA, Larson JL, Lauffer BE, Goldstein LD, Appling LL, Borneo J, Poon C, Ho T, Cai F, Steiner P, van der Brug MP, Modrusan Z, Kaminker JS, Hansen DV. Srinivasan K, et al. Among authors: larson jl. Nat Commun. 2016 Apr 21;7:11295. doi: 10.1038/ncomms11295. Nat Commun. 2016. PMID: 27097852 Free PMC article.
A Common Variant of IL-6R is Associated with Elevated IL-6 Pathway Activity in Alzheimer's Disease Brains.
Haddick PC, Larson JL, Rathore N, Bhangale TR, Phung QT, Srinivasan K, Hansen DV, Lill JR; Alzheimer’s Disease Genetic Consortium (ADGC), Alzheimer’s Disease Neuroimaging Initiative (ADNI); Pericak-Vance MA, Haines J, Farrer LA, Kauwe JS, Schellenberg GD, Cruchaga C, Goate AM, Behrens TW, Watts RJ, Graham RR, Kaminker JS, van der Brug M. Haddick PC, et al. Among authors: larson jl. J Alzheimers Dis. 2017;56(3):1037-1054. doi: 10.3233/JAD-160524. J Alzheimers Dis. 2017. PMID: 28106546 Free PMC article.
Dual leucine zipper kinase is required for excitotoxicity-induced neuronal degeneration.
Pozniak CD, Sengupta Ghosh A, Gogineni A, Hanson JE, Lee SH, Larson JL, Solanoy H, Bustos D, Li H, Ngu H, Jubb AM, Ayalon G, Wu J, Scearce-Levie K, Zhou Q, Weimer RM, Kirkpatrick DS, Lewcock JW. Pozniak CD, et al. Among authors: larson jl. J Exp Med. 2013 Nov 18;210(12):2553-67. doi: 10.1084/jem.20122832. Epub 2013 Oct 28. J Exp Med. 2013. PMID: 24166713 Free PMC article.
Moment based gene set tests.
Larson JL, Owen AB. Larson JL, et al. BMC Bioinformatics. 2015 Apr 28;16:132. doi: 10.1186/s12859-015-0571-7. BMC Bioinformatics. 2015. PMID: 25928861 Free PMC article.
209 results