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Impact of a five-dimensional framework on R&D productivity at AstraZeneca.
Morgan P, Brown DG, Lennard S, Anderton MJ, Barrett JC, Eriksson U, Fidock M, Hamrén B, Johnson A, March RE, Matcham J, Mettetal J, Nicholls DJ, Platz S, Rees S, Snowden MA, Pangalos MN. Morgan P, et al. Among authors: lennard s. Nat Rev Drug Discov. 2018 Mar;17(3):167-181. doi: 10.1038/nrd.2017.244. Epub 2018 Jan 19. Nat Rev Drug Discov. 2018. PMID: 29348681
Human monoclonal antibodies to the insulin-like growth factor 1 receptor inhibit receptor activation and tumor growth in preclinical studies.
Runnels HA, Arbuckle JA, Bailey KS, Nicastro PJ, Sun D, Pegg JA, Meyer DM, Evans M, Bono CP, Lie WR, Moffat MA, Casperson GF, Lennard S, Elvin J, Vaughan T, Smith CE, Morton PA. Runnels HA, et al. Among authors: lennard s. Adv Ther. 2010 Jul;27(7):458-75. doi: 10.1007/s12325-010-0026-5. Epub 2010 Jun 14. Adv Ther. 2010. PMID: 20574692
A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope.
Miller MD, Geleziunas R, Bianchi E, Lennard S, Hrin R, Zhang H, Lu M, An Z, Ingallinella P, Finotto M, Mattu M, Finnefrock AC, Bramhill D, Cook J, Eckert DM, Hampton R, Patel M, Jarantow S, Joyce J, Ciliberto G, Cortese R, Lu P, Strohl W, Schleif W, McElhaugh M, Lane S, Lloyd C, Lowe D, Osbourn J, Vaughan T, Emini E, Barbato G, Kim PS, Hazuda DJ, Shiver JW, Pessi A. Miller MD, et al. Among authors: lennard s. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14759-64. doi: 10.1073/pnas.0506927102. Epub 2005 Oct 3. Proc Natl Acad Sci U S A. 2005. PMID: 16203977 Free PMC article.
18 results