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Impact of a five-dimensional framework on R&D productivity at AstraZeneca.
Morgan P, Brown DG, Lennard S, Anderton MJ, Barrett JC, Eriksson U, Fidock M, Hamrén B, Johnson A, March RE, Matcham J, Mettetal J, Nicholls DJ, Platz S, Rees S, Snowden MA, Pangalos MN. Morgan P, et al. Among authors: matcham j. Nat Rev Drug Discov. 2018 Mar;17(3):167-181. doi: 10.1038/nrd.2017.244. Epub 2018 Jan 19. Nat Rev Drug Discov. 2018. PMID: 29348681
Decision-making in early clinical drug development.
Frewer P, Mitchell P, Watkins C, Matcham J. Frewer P, et al. Among authors: matcham j. Pharm Stat. 2016 May;15(3):255-63. doi: 10.1002/pst.1746. Epub 2016 Mar 17. Pharm Stat. 2016. PMID: 26991401
Guidelines for clinical trial protocols for interventions involving artificial intelligence: the SPIRIT-AI extension.
Cruz Rivera S, Liu X, Chan AW, Denniston AK, Calvert MJ; SPIRIT-AI and CONSORT-AI Working Group; SPIRIT-AI and CONSORT-AI Steering Group; SPIRIT-AI and CONSORT-AI Consensus Group. Cruz Rivera S, et al. Nat Med. 2020 Sep;26(9):1351-1363. doi: 10.1038/s41591-020-1037-7. Epub 2020 Sep 9. Nat Med. 2020. PMID: 32908284 Free PMC article. Review.
A statistician's perspective on biomarkers in drug development.
Jenkins M, Flynn A, Smart T, Harbron C, Sabin T, Ratnayake J, Delmar P, Herath A, Jarvis P, Matcham J; PSI Biomarker Special Interest Group. Jenkins M, et al. Among authors: matcham j. Pharm Stat. 2011 Nov-Dec;10(6):494-507. doi: 10.1002/pst.532. Epub 2011 Dec 8. Pharm Stat. 2011. PMID: 22162336 Review.
Missing data: discussion points from the PSI missing data expert group.
Burzykowski T, Carpenter J, Coens C, Evans D, France L, Kenward M, Lane P, Matcham J, Morgan D, Phillips A, Roger J, Sullivan B, White I, Yu LM; of the PSI Missing Data Expert Group. Burzykowski T, et al. Among authors: matcham j. Pharm Stat. 2010 Oct-Dec;9(4):288-97. doi: 10.1002/pst.391. Pharm Stat. 2010. PMID: 19844946
38 results