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Cytochrome b 5 impacts on cytochrome P450-mediated metabolism of benzo[a]pyrene and its DNA adduct formation: studies in hepatic cytochrome b 5 /P450 reductase null (HBRN) mice.
Reed L, Mrizova I, Barta F, Indra R, Moserova M, Kopka K, Schmeiser HH, Wolf CR, Henderson CJ, Stiborova M, Phillips DH, Arlt VM. Reed L, et al. Among authors: kopka k. Arch Toxicol. 2018 Apr;92(4):1625-1638. doi: 10.1007/s00204-018-2162-7. Epub 2018 Jan 24. Arch Toxicol. 2018. PMID: 29368147 Free PMC article.
The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice.
Krais AM, Speksnijder EN, Melis JP, Indra R, Moserova M, Godschalk RW, van Schooten FJ, Seidel A, Kopka K, Schmeiser HH, Stiborova M, Phillips DH, Luijten M, Arlt VM. Krais AM, et al. Among authors: kopka k. Arch Toxicol. 2016 Apr;90(4):839-51. doi: 10.1007/s00204-015-1531-8. Epub 2015 May 21. Arch Toxicol. 2016. PMID: 25995008 Free PMC article.
Epoxyeicosatrienoic acids (EETs) form adducts with DNA in vitro.
Funk DJ, Sorg BL, Kopka K, Schmeiser HH. Funk DJ, et al. Among authors: kopka k. Prostaglandins Other Lipid Mediat. 2016 Mar;123:63-7. doi: 10.1016/j.prostaglandins.2016.04.006. Epub 2016 May 7. Prostaglandins Other Lipid Mediat. 2016. PMID: 27166927
NADH:Cytochrome b5 Reductase and Cytochrome b5 Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene.
Stiborová M, Indra R, Moserová M, Frei E, Schmeiser HH, Kopka K, Phillips DH, Arlt VM. Stiborová M, et al. Among authors: kopka k. Chem Res Toxicol. 2016 Aug 15;29(8):1325-34. doi: 10.1021/acs.chemrestox.6b00143. Epub 2016 Jul 20. Chem Res Toxicol. 2016. PMID: 27404282 Free PMC article.
Impact of genetic modulation of SULT1A enzymes on DNA adduct formation by aristolochic acids and 3-nitrobenzanthrone.
Arlt VM, Meinl W, Florian S, Nagy E, Barta F, Thomann M, Mrizova I, Krais AM, Liu M, Richards M, Mirza A, Kopka K, Phillips DH, Glatt H, Stiborova M, Schmeiser HH. Arlt VM, et al. Among authors: kopka k. Arch Toxicol. 2017 Apr;91(4):1957-1975. doi: 10.1007/s00204-016-1808-6. Epub 2016 Aug 24. Arch Toxicol. 2017. PMID: 27557898 Free PMC article.
Correction to NADH:Cytochrome b5 Reductase and Cytochrome b5 Can Act as Sole Electron Donors to Human Cytochrome P450 1A1-Mediated Oxidation and DNA Adduct Formation by Benzo[a]pyrene.
Stiborová M, Indra R, Moserová M, Frei E, Schmeiser HH, Kopka K, Phillips DH, Arlt VM. Stiborová M, et al. Among authors: kopka k. Chem Res Toxicol. 2016 Sep 19;29(9):1571. doi: 10.1021/acs.chemrestox.6b00283. Epub 2016 Aug 30. Chem Res Toxicol. 2016. PMID: 27575721 Free PMC article. No abstract available.
251 results