Hamelin J - Search Results

1

New Sequencing technologies help revealing unexpected mutations in Autosomal Dominant Hypercholesterolemia.

Elbitar S, Susan-Resiga D, Ghaleb Y, El Khoury P, Peloso G, Stitziel N, Rabès JP, Carreau V, Hamelin J, Ben-Djoudi-Ouadda A, Bruckert E, Boileau C, Seidah NG, Varret M, Abifadel M. Elbitar S, et al. Among authors: hamelin j. Sci Rep. 2018 Jan 31;8(1):1943. doi: 10.1038/s41598-018-20281-9. Sci Rep. 2018. PMID: 29386597 Free PMC article.

2

Testicular expression of PC4 in the rat: molecular diversity of a novel germ cell-specific Kex2/subtilisin-like proprotein convertase.

Seidah NG, Day R, Hamelin J, Gaspar A, Collard MW, Chrétien M. Seidah NG, et al. Among authors: hamelin j. Mol Endocrinol. 1992 Oct;6(10):1559-70. doi: 10.1210/mend.6.10.1448111. Mol Endocrinol. 1992. PMID: 1448111

3

The cDNA sequence of the human pro-hormone and pro-protein convertase PC1.

Seidah NG, Hamelin J, Gaspar AM, Day R, Chrétien M. Seidah NG, et al. Among authors: hamelin j. DNA Cell Biol. 1992 May;11(4):283-9. doi: 10.1089/dna.1992.11.283. DNA Cell Biol. 1992. PMID: 1605851

4

Structure-function studies on the biosynthesis and bioactivity of the precursor convertase PC2 and the formation of the PC2/7B2 complex.

Benjannet S, Lusson J, Hamelin J, Savaria D, Chrétien M, Seidah NG. Benjannet S, et al. Among authors: hamelin j. FEBS Lett. 1995 Apr 3;362(2):151-5. doi: 10.1016/0014-5793(95)00228-2. FEBS Lett. 1995. PMID: 7720862 Free article.

5

cDNA structure of the mouse and rat subtilisin/kexin-like PC5: a candidate proprotein convertase expressed in endocrine and nonendocrine cells.

Lusson J, Vieau D, Hamelin J, Day R, Chrétien M, Seidah NG. Lusson J, et al. Among authors: hamelin j. Proc Natl Acad Sci U S A. 1993 Jul 15;90(14):6691-5. doi: 10.1073/pnas.90.14.6691. Proc Natl Acad Sci U S A. 1993. PMID: 8341687 Free PMC article.

6

The integrity of the RRGDL sequence of the proprotein convertase PC1 is critical for its zymogen and C-terminal processing and for its cellular trafficking.

Lusson J, Benjannet S, Hamelin J, Savaria D, Chrétien M, Seidah NG. Lusson J, et al. Among authors: hamelin j. Biochem J. 1997 Sep 15;326 ( Pt 3)(Pt 3):737-44. doi: 10.1042/bj3260737. Biochem J. 1997. PMID: 9307023 Free PMC article.

7

Residues unique to the pro-hormone convertase PC2 modulate its autoactivation, binding to 7B2 and enzymatic activity.

Benjannet S, Mamarbachi AM, Hamelin J, Savaria D, Munzer JS, Chrétien M, Seidah NG. Benjannet S, et al. Among authors: hamelin j. FEBS Lett. 1998 May 22;428(1-2):37-42. doi: 10.1016/s0014-5793(98)00480-3. FEBS Lett. 1998. PMID: 9645470 Free article.

8

The subtilisin/kexin family of precursor convertases. Emphasis on PC1, PC2/7B2, POMC and the novel enzyme SKI-1.

Seidah NG, Benjannet S, Hamelin J, Mamarbachi AM, Basak A, Marcinkiewicz J, Mbikay M, Chrétien M, Marcinkiewicz M. Seidah NG, et al. Among authors: hamelin j. Ann N Y Acad Sci. 1999 Oct 20;885:57-74. doi: 10.1111/j.1749-6632.1999.tb08665.x. Ann N Y Acad Sci. 1999. PMID: 10816641 Review.

9

NARC-1/PCSK9 and its natural mutants: zymogen cleavage and effects on the low density lipoprotein (LDL) receptor and LDL cholesterol.

Benjannet S, Rhainds D, Essalmani R, Mayne J, Wickham L, Jin W, Asselin MC, Hamelin J, Varret M, Allard D, Trillard M, Abifadel M, Tebon A, Attie AD, Rader DJ, Boileau C, Brissette L, Chrétien M, Prat A, Seidah NG. Benjannet S, et al. Among authors: hamelin j. J Biol Chem. 2004 Nov 19;279(47):48865-75. doi: 10.1074/jbc.M409699200. Epub 2004 Sep 9. J Biol Chem. 2004. PMID: 15358785 Free article.

10

Implication of proprotein convertases in the processing and spread of severe acute respiratory syndrome coronavirus.

Bergeron E, Vincent MJ, Wickham L, Hamelin J, Basak A, Nichol ST, Chrétien M, Seidah NG. Bergeron E, et al. Among authors: hamelin j. Biochem Biophys Res Commun. 2005 Jan 21;326(3):554-63. doi: 10.1016/j.bbrc.2004.11.063. Biochem Biophys Res Commun. 2005. PMID: 15596135 Free PMC article.

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