Poutanen M - Search Results

1

Hydroxysteroid (17β) dehydrogenase 13 deficiency triggers hepatic steatosis and inflammation in mice.

Adam M, Heikelä H, Sobolewski C, Portius D, Mäki-Jouppila J, Mehmood A, Adhikari P, Esposito I, Elo LL, Zhang FP, Ruohonen ST, Strauss L, Foti M, Poutanen M. Adam M, et al. Among authors: poutanen m. FASEB J. 2018 Jun;32(6):3434-3447. doi: 10.1096/fj.201700914R. Epub 2018 Jan 31. FASEB J. 2018. PMID: 29401633

Our data indicate that disruption of Hsd17b13 impairs hepatic-lipid metabolism in mice, resulting in liver steatosis and inflammation, but the enzyme does not play a major role in the regulation of reproductive functions.-Adam, M., Heikela, H., Sobolewski, C., Portius, D., …

Our data indicate that disruption of Hsd17b13 impairs hepatic-lipid metabolism in mice, resulting in liver steatosis and inflammation, but t …

2

Inhibition of 17beta-hydroxysteroid oxidoreductase by flavonoids in breast and prostate cancer cells.

Mäkelä S, Poutanen M, Kostian ML, Lehtimäki N, Strauss L, Santti R, Vihko R. Mäkelä S, et al. Among authors: poutanen m. Proc Soc Exp Biol Med. 1998 Mar;217(3):310-6. doi: 10.3181/00379727-217-44237. Proc Soc Exp Biol Med. 1998. PMID: 9492340

3

Normal prenatal but arrested postnatal sexual development of luteinizing hormone receptor knockout (LuRKO) mice.

Zhang FP, Poutanen M, Wilbertz J, Huhtaniemi I. Zhang FP, et al. Among authors: poutanen m. Mol Endocrinol. 2001 Jan;15(1):172-83. doi: 10.1210/mend.15.1.0582. Mol Endocrinol. 2001. PMID: 11145748

4

The low gonadotropin-independent constitutive production of testicular testosterone is sufficient to maintain spermatogenesis.

Zhang FP, Pakarainen T, Poutanen M, Toppari J, Huhtaniemi I. Zhang FP, et al. Among authors: poutanen m. Proc Natl Acad Sci U S A. 2003 Nov 11;100(23):13692-7. doi: 10.1073/pnas.2232815100. Epub 2003 Oct 29. Proc Natl Acad Sci U S A. 2003. PMID: 14585929 Free PMC article.

5

Molecular characterization of postnatal development of testicular steroidogenesis in luteinizing hormone receptor knockout mice.

Zhang FP, Pakarainen T, Zhu F, Poutanen M, Huhtaniemi I. Zhang FP, et al. Among authors: poutanen m. Endocrinology. 2004 Mar;145(3):1453-63. doi: 10.1210/en.2003-1049. Epub 2003 Nov 26. Endocrinology. 2004. PMID: 14645113

6

Multiple structural and functional abnormalities in the p450 aromatase expressing transgenic male mice are ameliorated by a p450 aromatase inhibitor.

Li X, Strauss L, Mäkelä S, Streng T, Huhtaniemi I, Santti R, Poutanen M. Li X, et al. Among authors: poutanen m. Am J Pathol. 2004 Mar;164(3):1039-48. doi: 10.1016/S0002-9440(10)63191-4. Am J Pathol. 2004. PMID: 14982857 Free PMC article.

7

Testosterone replacement therapy induces spermatogenesis and partially restores fertility in luteinizing hormone receptor knockout mice.

Pakarainen T, Zhang FP, Mäkelä S, Poutanen M, Huhtaniemi I. Pakarainen T, et al. Among authors: poutanen m. Endocrinology. 2005 Feb;146(2):596-606. doi: 10.1210/en.2004-0913. Epub 2004 Oct 28. Endocrinology. 2005. PMID: 15514086

8

Knockout of luteinizing hormone receptor abolishes the effects of follicle-stimulating hormone on preovulatory maturation and ovulation of mouse graafian follicles.

Pakarainen T, Zhang FP, Nurmi L, Poutanen M, Huhtaniemi I. Pakarainen T, et al. Among authors: poutanen m. Mol Endocrinol. 2005 Oct;19(10):2591-602. doi: 10.1210/me.2005-0075. Epub 2005 Jun 7. Mol Endocrinol. 2005. PMID: 15941853

9

Fertility in luteinizing hormone receptor-knockout mice after wild-type ovary transplantation demonstrates redundancy of extragonadal luteinizing hormone action.

Pakarainen T, Zhang FP, Poutanen M, Huhtaniemi I. Pakarainen T, et al. Among authors: poutanen m. J Clin Invest. 2005 Jul;115(7):1862-8. doi: 10.1172/JCI24562. Epub 2005 Jun 9. J Clin Invest. 2005. PMID: 15951841 Free PMC article.

10

Transgenic mice expressing p450 aromatase as a model for male infertility associated with chronic inflammation in the testis.

Li X, Strauss L, Kaatrasalo A, Mayerhofer A, Huhtaniemi I, Santti R, Mäkelä S, Poutanen M. Li X, et al. Among authors: poutanen m. Endocrinology. 2006 Mar;147(3):1271-7. doi: 10.1210/en.2005-0654. Epub 2005 Nov 23. Endocrinology. 2006. PMID: 16306085

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