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Brief Report: The Genetic Profile of Rheumatoid Factor-Positive Polyarticular Juvenile Idiopathic Arthritis Resembles That of Adult Rheumatoid Arthritis.
Hinks A, Marion MC, Cobb J, Comeau ME, Sudman M, Ainsworth HC, Bowes J; Juvenile Idiopathic Arthritis Consortium for Immunochip; Becker ML, Bohnsack JF, Haas JP, Lovell DJ, Mellins ED, Nelson JL, Nordal E, Punaro M, Reed AM, Rose CD, Rosenberg AM, Rygg M, Smith SL, Stevens AM, Videm V, Wallace CA, Wedderburn LR, Yarwood A, Yeung RSM, Langefeld CD, Thompson SD, Thomson W, Prahalad S. Hinks A, et al. Among authors: smith sl. Arthritis Rheumatol. 2018 Jun;70(6):957-962. doi: 10.1002/art.40443. Epub 2018 Apr 21. Arthritis Rheumatol. 2018. PMID: 29426059 Free PMC article.
Investigating CD11c expression as a potential genomic biomarker of response to TNF inhibitor biologics in whole blood rheumatoid arthritis samples.
Smith SL, Eyre S, Yarwood A, Hyrich K, Morgan AW, Wilson AG, Isaacs J; Biologics in Rheumatoid Arthritis Genetics and Genomics Study Syndicate 6; Plant D, Barton A. Smith SL, et al. Arthritis Res Ther. 2015 Dec 14;17:359. doi: 10.1186/s13075-015-0868-y. Arthritis Res Ther. 2015. PMID: 26667261 Free PMC article.
Fine-mapping the MHC locus in juvenile idiopathic arthritis (JIA) reveals genetic heterogeneity corresponding to distinct adult inflammatory arthritic diseases.
Hinks A, Bowes J, Cobb J, Ainsworth HC, Marion MC, Comeau ME, Sudman M, Han B; Juvenile Arthritis Consortium for Immunochip; Becker ML, Bohnsack JF, de Bakker PI, Haas JP, Hazen M, Lovell DJ, Nigrovic PA, Nordal E, Punnaro M, Rosenberg AM, Rygg M, Smith SL, Wise CA, Videm V, Wedderburn LR, Yarwood A, Yeung RS, Prahalad S, Langefeld CD, Raychaudhuri S, Thompson SD, Thomson W. Hinks A, et al. Among authors: smith sl. Ann Rheum Dis. 2017 Apr;76(4):765-772. doi: 10.1136/annrheumdis-2016-210025. Epub 2016 Dec 20. Ann Rheum Dis. 2017. PMID: 27998952 Free PMC article.
Profiling of Gene Expression Biomarkers as a Classifier of Methotrexate Nonresponse in Patients With Rheumatoid Arthritis.
Plant D, Maciejewski M, Smith S, Nair N; Maximising Therapeutic Utility in Rheumatoid Arthritis Consortium, the RAMS Study Group; Hyrich K, Ziemek D, Barton A, Verstappen S. Plant D, et al. Arthritis Rheumatol. 2019 May;71(5):678-684. doi: 10.1002/art.40810. Epub 2019 Mar 19. Arthritis Rheumatol. 2019. PMID: 30615300 Free PMC article.
Genomic risk scores for juvenile idiopathic arthritis and its subtypes.
Cánovas R, Cobb J, Brozynska M, Bowes J, Li YR, Smith SL, Hakonarson H, Thomson W, Ellis JA, Abraham G, Munro JE, Inouye M. Cánovas R, et al. Among authors: smith sl. Ann Rheum Dis. 2020 Dec;79(12):1572-1579. doi: 10.1136/annrheumdis-2020-217421. Epub 2020 Sep 4. Ann Rheum Dis. 2020. PMID: 32887683 Free PMC article.
Combined genetic analysis of juvenile idiopathic arthritis clinical subtypes identifies novel risk loci, target genes and key regulatory mechanisms.
López-Isac E, Smith SL, Marion MC, Wood A, Sudman M, Yarwood A, Shi C, Gaddi VP, Martin P, Prahalad S, Eyre S, Orozco G, Morris AP, Langefeld CD, Thompson SD, Thomson W, Bowes J. López-Isac E, et al. Among authors: smith sl. Ann Rheum Dis. 2021 Mar;80(3):321-328. doi: 10.1136/annrheumdis-2020-218481. Epub 2020 Oct 26. Ann Rheum Dis. 2021. PMID: 33106285 Free PMC article.
Patient-reported wellbeing and clinical disease measures over time captured by multivariate trajectories of disease activity in individuals with juvenile idiopathic arthritis in the UK: a multicentre prospective longitudinal study.
Shoop-Worrall SJW, Hyrich KL, Wedderburn LR, Thomson W, Geifman N; CAPS the CLUSTER Consortium. Shoop-Worrall SJW, et al. Lancet Rheumatol. 2020 Dec 4;3(2):e111-e121. doi: 10.1016/S2665-9913(20)30269-1. eCollection 2021 Feb. Lancet Rheumatol. 2020. PMID: 33554133 Free PMC article.
No evidence that genetic predictors of susceptibility predict changes in core outcomes in JIA.
Yarwood A, Shoop-Worrall S, López-Isac E, Smith SL, Morris AP; Childhood Arthritis Prospective Study (CAPS) group; Bowes JD, Tordoff M, Hyrich KL, Thomson W, Eyre S. Yarwood A, et al. Among authors: smith sl. Rheumatology (Oxford). 2022 Oct 6;61(10):4136-4144. doi: 10.1093/rheumatology/keab942. Rheumatology (Oxford). 2022. PMID: 35015833 Free PMC article.
832 results