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Neutron and Atomic Resolution X-ray Structures of a Lytic Polysaccharide Monooxygenase Reveal Copper-Mediated Dioxygen Binding and Evidence for N-Terminal Deprotonation.
Bacik JP, Mekasha S, Forsberg Z, Kovalevsky AY, Vaaje-Kolstad G, Eijsink VGH, Nix JC, Coates L, Cuneo MJ, Unkefer CJ, Chen JC. Bacik JP, et al. Among authors: cuneo mj. Biochemistry. 2017 May 23;56(20):2529-2532. doi: 10.1021/acs.biochem.7b00019. Epub 2017 May 11. Biochemistry. 2017. PMID: 28481095
Neutron and high-resolution room-temperature X-ray data collection from crystallized lytic polysaccharide monooxygenase.
Bacik JP, Mekasha S, Forsberg Z, Kovalevsky A, Nix JC, Cuneo MJ, Coates L, Vaaje-Kolstad G, Chen JC, Eijsink VG, Unkefer CJ. Bacik JP, et al. Among authors: cuneo mj. Acta Crystallogr F Struct Biol Commun. 2015 Nov;71(Pt 11):1448-52. doi: 10.1107/S2053230X15019743. Epub 2015 Oct 30. Acta Crystallogr F Struct Biol Commun. 2015. PMID: 26527275 Free PMC article.
Capturing snapshots of APE1 processing DNA damage.
Freudenthal BD, Beard WA, Cuneo MJ, Dyrkheeva NS, Wilson SH. Freudenthal BD, et al. Among authors: cuneo mj. Nat Struct Mol Biol. 2015 Nov;22(11):924-31. doi: 10.1038/nsmb.3105. Epub 2015 Oct 12. Nat Struct Mol Biol. 2015. PMID: 26458045 Free PMC article.
Modulating Enzyme Activity by Altering Protein Dynamics with Solvent.
Duff MR Jr, Borreguero JM, Cuneo MJ, Ramanathan A, He J, Kamath G, Chennubhotla SC, Meilleur F, Howell EE, Herwig KW, Myles DAA, Agarwal PK. Duff MR Jr, et al. Among authors: cuneo mj. Biochemistry. 2018 Jul 24;57(29):4263-4275. doi: 10.1021/acs.biochem.8b00424. Epub 2018 Jul 6. Biochemistry. 2018. PMID: 29901984 Free PMC article.
55 results