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4'-Demethylnobiletin, a bioactive metabolite of nobiletin enhancing PKA/ERK/CREB signaling, rescues learning impairment associated with NMDA receptor antagonism via stimulation of the ERK cascade.
Al Rahim M, Nakajima A, Saigusa D, Tetsu N, Maruyama Y, Shibuya M, Yamakoshi H, Tomioka Y, Iwabuchi Y, Ohizumi Y, Yamakuni T. Al Rahim M, et al. Among authors: tomioka y. Biochemistry. 2009 Aug 18;48(32):7713-21. doi: 10.1021/bi901088w. Biochemistry. 2009. PMID: 19601643
Identification of novel biomarkers of hepatocellular carcinoma by high-definition mass spectrometry: Ultrahigh-performance liquid chromatography quadrupole time-of-flight mass spectrometry and desorption electrospray ionization mass spectrometry imaging.
Nagai K, Uranbileg B, Chen Z, Fujioka A, Yamazaki T, Matsumoto Y, Tsukamoto H, Ikeda H, Yatomi Y, Chiba H, Hui SP, Nakazawa T, Saito R, Koshiba S, Aoki J, Saigusa D, Tomioka Y. Nagai K, et al. Among authors: tomioka y. Rapid Commun Mass Spectrom. 2020 Apr;34 Suppl 1(Suppl 1):e8551. doi: 10.1002/rcm.8551. Epub 2019 Nov 6. Rapid Commun Mass Spectrom. 2020. PMID: 31412144 Free PMC article.
Comprehensive and semi-quantitative analysis of carboxyl-containing metabolites related to gut microbiota on chronic kidney disease using 2-picolylamine isotopic labeling LC-MS/MS.
Kanemitsu Y, Mishima E, Maekawa M, Matsumoto Y, Saigusa D, Yamaguchi H, Ogura J, Tsukamoto H, Tomioka Y, Abe T, Mano N. Kanemitsu Y, et al. Among authors: tomioka y. Sci Rep. 2019 Dec 13;9(1):19075. doi: 10.1038/s41598-019-55600-1. Sci Rep. 2019. PMID: 31836785 Free PMC article.
Nrf2 plays a critical role in the metabolic response during and after spaceflight.
Uruno A, Saigusa D, Suzuki T, Yumoto A, Nakamura T, Matsukawa N, Yamazaki T, Saito R, Taguchi K, Suzuki M, Suzuki N, Otsuki A, Katsuoka F, Hishinuma E, Okada R, Koshiba S, Tomioka Y, Shimizu R, Shirakawa M, Kensler TW, Shiba D, Yamamoto M. Uruno A, et al. Among authors: tomioka y. Commun Biol. 2021 Dec 9;4(1):1381. doi: 10.1038/s42003-021-02904-6. Commun Biol. 2021. PMID: 34887485 Free PMC article.
Simultaneous quantitative analysis of uremic toxins by LC-MS/MS with a reversed-phase/cation-exchange/anion-exchange tri-modal mixed-mode column.
Kanemitsu Y, Asaji K, Matsumoto Y, Tsukamoto H, Saigusa D, Mukawa C, Tachikawa T, Abe T, Tomioka Y. Kanemitsu Y, et al. Among authors: tomioka y. J Chromatogr B Analyt Technol Biomed Life Sci. 2017 Nov 15;1068-1069:1-8. doi: 10.1016/j.jchromb.2017.10.009. Epub 2017 Oct 5. J Chromatogr B Analyt Technol Biomed Life Sci. 2017. PMID: 29024911
382 results