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Inhibition of Endothelial NOTCH1 Signaling Attenuates Inflammation by Reducing Cytokine-Mediated Histone Acetylation at Inflammatory Enhancers.
Poulsen LC, Edelmann RJ, Krüger S, Diéguez-Hurtado R, Shah A, Stav-Noraas TE, Renzi A, Szymanska M, Wang J, Ehling M, Benedito R, Kasprzycka M, Bækkevold E, Sundnes O, Midwood KS, Scott H, Collas P, Siebel CW, Adams RH, Haraldsen G, Sundlisæter E, Hol J. Poulsen LC, et al. Among authors: siebel cw. Arterioscler Thromb Vasc Biol. 2018 Apr;38(4):854-869. doi: 10.1161/ATVBAHA.117.310388. Epub 2018 Feb 15. Arterioscler Thromb Vasc Biol. 2018. PMID: 29449332
Endothelial Notch1 Activity Facilitates Metastasis.
Wieland E, Rodriguez-Vita J, Liebler SS, Mogler C, Moll I, Herberich SE, Espinet E, Herpel E, Menuchin A, Chang-Claude J, Hoffmeister M, Gebhardt C, Brenner H, Trumpp A, Siebel CW, Hecker M, Utikal J, Sprinzak D, Fischer A. Wieland E, et al. Among authors: siebel cw. Cancer Cell. 2017 Mar 13;31(3):355-367. doi: 10.1016/j.ccell.2017.01.007. Epub 2017 Feb 23. Cancer Cell. 2017. PMID: 28238683 Free article.
NOTCH1 and NOTCH2 regulate epithelial cell proliferation in mouse and human gastric corpus.
Demitrack ES, Gifford GB, Keeley TM, Horita N, Todisco A, Turgeon DK, Siebel CW, Samuelson LC. Demitrack ES, et al. Among authors: siebel cw. Am J Physiol Gastrointest Liver Physiol. 2017 Feb 1;312(2):G133-G144. doi: 10.1152/ajpgi.00325.2016. Epub 2016 Dec 8. Am J Physiol Gastrointest Liver Physiol. 2017. PMID: 27932500 Free PMC article.
Notch-1 Inhibition Promotes Immune Regulation in Transplantation Via Regulatory T Cell-Dependent Mechanisms.
Magee CN, Murakami N, Borges TJ, Shimizu T, Safa K, Ohori S, Cai S, Uffing A, Azzi J, Elyaman W, Charbonnier LM, Liu K, Toprak D, Visner G, Chatila TA, Siebel CW, Najafian N, Riella LV. Magee CN, et al. Among authors: siebel cw. Circulation. 2019 Sep 9;140(10):846-863. doi: 10.1161/CIRCULATIONAHA.119.040563. Epub 2019 Jul 3. Circulation. 2019. PMID: 31266349 Free PMC article.
Modulation of Notch1 signaling regulates bone fracture healing.
Novak S, Roeder E, Sinder BP, Adams DJ, Siebel CW, Grcevic D, Hankenson KD, Matthews BG, Kalajzic I. Novak S, et al. Among authors: siebel cw. J Orthop Res. 2020 Nov;38(11):2350-2361. doi: 10.1002/jor.24650. Epub 2020 Mar 16. J Orthop Res. 2020. PMID: 32141629 Free PMC article.
Notch signalling drives synovial fibroblast identity and arthritis pathology.
Wei K, Korsunsky I, Marshall JL, Gao A, Watts GFM, Major T, Croft AP, Watts J, Blazar PE, Lange JK, Thornhill TS, Filer A, Raza K, Donlin LT; Accelerating Medicines Partnership Rheumatoid Arthritis & Systemic Lupus Erythematosus (AMP RA/SLE) Consortium; Siebel CW, Buckley CD, Raychaudhuri S, Brenner MB. Wei K, et al. Among authors: siebel cw. Nature. 2020 Jun;582(7811):259-264. doi: 10.1038/s41586-020-2222-z. Epub 2020 Apr 22. Nature. 2020. PMID: 32499639 Free PMC article.
Developing HSCs become Notch independent by the end of maturation in the AGM region.
Souilhol C, Lendinez JG, Rybtsov S, Murphy F, Wilson H, Hills D, Batsivari A, Binagui-Casas A, McGarvey AC, MacDonald HR, Kageyama R, Siebel C, Zhao S, Medvinsky A. Souilhol C, et al. Blood. 2016 Sep 22;128(12):1567-77. doi: 10.1182/blood-2016-03-708164. Epub 2016 Jul 15. Blood. 2016. PMID: 27421959 Free PMC article.
68 results