Luesch H - Search Results

1

Rational engineering of Streptomyces albus J1074 for the overexpression of secondary metabolite gene clusters.

Kallifidas D, Jiang G, Ding Y, Luesch H. Kallifidas D, et al. Among authors: luesch h. Microb Cell Fact. 2018 Feb 17;17(1):25. doi: 10.1186/s12934-018-0874-2. Microb Cell Fact. 2018. PMID: 29454348 Free PMC article.

2

Halogenated Phenazines that Potently Eradicate Biofilms, MRSA Persister Cells in Non-Biofilm Cultures, and Mycobacterium tuberculosis.

Garrison AT, Abouelhassan Y, Kallifidas D, Bai F, Ukhanova M, Mai V, Jin S, Luesch H, Huigens RW 3rd. Garrison AT, et al. Among authors: luesch h. Angew Chem Int Ed Engl. 2015 Dec 1;54(49):14819-23. doi: 10.1002/anie.201508155. Epub 2015 Oct 20. Angew Chem Int Ed Engl. 2015. PMID: 26480852

3

Structure-Activity Relationships of a Diverse Class of Halogenated Phenazines That Targets Persistent, Antibiotic-Tolerant Bacterial Biofilms and Mycobacterium tuberculosis.

Garrison AT, Abouelhassan Y, Norwood VM 4th, Kallifidas D, Bai F, Nguyen MT, Rolfe M, Burch GM, Jin S, Luesch H, Huigens RW 3rd. Garrison AT, et al. Among authors: luesch h. J Med Chem. 2016 Apr 28;59(8):3808-25. doi: 10.1021/acs.jmedchem.5b02004. Epub 2016 Apr 6. J Med Chem. 2016. PMID: 27018907

4

A Highly Potent Class of Halogenated Phenazine Antibacterial and Biofilm-Eradicating Agents Accessed Through a Modular Wohl-Aue Synthesis.

Yang H, Abouelhassan Y, Burch GM, Kallifidas D, Huang G, Yousaf H, Jin S, Luesch H, Huigens RW. Yang H, et al. Among authors: luesch h. Sci Rep. 2017 May 17;7(1):2003. doi: 10.1038/s41598-017-01045-3. Sci Rep. 2017. PMID: 28515440 Free PMC article.

5

Cyanobacterial Sfp-type phosphopantetheinyl transferases functionalize carrier proteins of diverse biosynthetic pathways.

Yang G, Zhang Y, Lee NK, Cozad MA, Kearney SE, Luesch H, Ding Y. Yang G, et al. Among authors: luesch h. Sci Rep. 2017 Sep 19;7(1):11888. doi: 10.1038/s41598-017-12244-3. Sci Rep. 2017. PMID: 28928426 Free PMC article.

6

Photosynthetic Production of Sunscreen Shinorine Using an Engineered Cyanobacterium.

Yang G, Cozad MA, Holland DA, Zhang Y, Luesch H, Ding Y. Yang G, et al. Among authors: luesch h. ACS Synth Biol. 2018 Feb 16;7(2):664-671. doi: 10.1021/acssynbio.7b00397. Epub 2018 Jan 19. ACS Synth Biol. 2018. PMID: 29304277

7

High-Yield Production of Herbicidal Thaxtomins and Thaxtomin Analogs in a Nonpathogenic Streptomyces Strain.

Jiang G, Zhang Y, Powell MM, Zhang P, Zuo R, Zhang Y, Kallifidas D, Tieu AM, Luesch H, Loria R, Ding Y. Jiang G, et al. Among authors: luesch h. Appl Environ Microbiol. 2018 May 17;84(11):e00164-18. doi: 10.1128/AEM.00164-18. Print 2018 Jun 1. Appl Environ Microbiol. 2018. PMID: 29602787 Free PMC article.

8

An Efficient Buchwald-Hartwig/Reductive Cyclization for the Scaffold Diversification of Halogenated Phenazines: Potent Antibacterial Targeting, Biofilm Eradication, and Prodrug Exploration.

Garrison AT, Abouelhassan Y, Kallifidas D, Tan H, Kim YS, Jin S, Luesch H, Huigens RW 3rd. Garrison AT, et al. Among authors: luesch h. J Med Chem. 2018 May 10;61(9):3962-3983. doi: 10.1021/acs.jmedchem.7b01903. Epub 2018 Apr 19. J Med Chem. 2018. PMID: 29638121

9

Chemical and Metagenomic Studies of the Lethal Black Band Disease of Corals Reveal Two Broadly Distributed, Redox-Sensitive Mixed Polyketide/Peptide Macrocycles.

Gunasekera SP, Meyer JL, Ding Y, Abboud KA, Luo D, Campbell JE, Angerhofer A, Goodsell JL, Raymundo LJ, Liu J, Ye T, Luesch H, Teplitski M, Paul VJ. Gunasekera SP, et al. Among authors: luesch h. J Nat Prod. 2019 Jan 25;82(1):111-121. doi: 10.1021/acs.jnatprod.8b00804. Epub 2019 Jan 13. J Nat Prod. 2019. PMID: 30636420 Free PMC article.

10

Fungal Epithiodiketopiperazines Carrying α,β-Polysulfide Bridges from Penicillium steckii YE, and Their Chemical Interconversion.

Jiang G, Zhang P, Ratnayake R, Yang G, Zhang Y, Zuo R, Powell M, Huguet-Tapia JC, Abboud KA, Dang LH, Teplitski M, Paul V, Xiao R, Ahammad KH, Zaman U, Hu Z, Cao S, Luesch H, Ding Y. Jiang G, et al. Among authors: luesch h. Chembiochem. 2021 Jan 15;22(2):416-422. doi: 10.1002/cbic.202000403. Epub 2020 Sep 30. Chembiochem. 2021. PMID: 32816319 Free PMC article.

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