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Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer.
Watt MJ, Clark AK, Selth LA, Haynes VR, Lister N, Rebello R, Porter LH, Niranjan B, Whitby ST, Lo J, Huang C, Schittenhelm RB, Anderson KE, Furic L, Wijayaratne PR, Matzaris M, Montgomery MK, Papargiris M, Norden S, Febbraio M, Risbridger GP, Frydenberg M, Nomura DK, Taylor RA. Watt MJ, et al. Among authors: nomura dk. Sci Transl Med. 2019 Feb 6;11(478):eaau5758. doi: 10.1126/scitranslmed.aau5758. Sci Transl Med. 2019. PMID: 30728288
Lipid metabolism in cancer.
Nomura DK, Cravatt BF. Nomura DK, et al. Biochim Biophys Acta. 2013 Oct;1831(10):1497-8. doi: 10.1016/j.bbalip.2013.08.001. Epub 2013 Aug 3. Biochim Biophys Acta. 2013. PMID: 23921253 No abstract available.
Unbiased Proteomic Profiling Uncovers a Targetable GNAS/PKA/PP2A Axis in Small Cell Lung Cancer Stem Cells.
Coles GL, Cristea S, Webber JT, Levin RS, Moss SM, He A, Sangodkar J, Hwang YC, Arand J, Drainas AP, Mooney NA, Demeter J, Spradlin JN, Mauch B, Le V, Shue YT, Ko JH, Lee MC, Kong C, Nomura DK, Ohlmeyer M, Swaney DL, Krogan NJ, Jackson PK, Narla G, Gordan JD, Shokat KM, Sage J. Coles GL, et al. Among authors: nomura dk. Cancer Cell. 2020 Jul 13;38(1):129-143.e7. doi: 10.1016/j.ccell.2020.05.003. Epub 2020 Jun 11. Cancer Cell. 2020. PMID: 32531271 Free PMC article.
Integrated phenotypic and activity-based profiling links Ces3 to obesity and diabetes.
Dominguez E, Galmozzi A, Chang JW, Hsu KL, Pawlak J, Li W, Godio C, Thomas J, Partida D, Niessen S, O'Brien PE, Russell AP, Watt MJ, Nomura DK, Cravatt BF, Saez E. Dominguez E, et al. Among authors: nomura dk. Nat Chem Biol. 2014 Feb;10(2):113-21. doi: 10.1038/nchembio.1429. Epub 2013 Dec 22. Nat Chem Biol. 2014. PMID: 24362705 Free PMC article.
Mechanisms linking obesity and cancer.
Louie SM, Roberts LS, Nomura DK. Louie SM, et al. Among authors: nomura dk. Biochim Biophys Acta. 2013 Oct;1831(10):1499-508. doi: 10.1016/j.bbalip.2013.02.008. Epub 2013 Mar 5. Biochim Biophys Acta. 2013. PMID: 23470257 Free PMC article. Review.
178 results