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Killer cell immunoglobulin-like receptor 3DL1 variation modifies HLA-B*57 protection against HIV-1.
Martin MP, Naranbhai V, Shea PR, Qi Y, Ramsuran V, Vince N, Gao X, Thomas R, Brumme ZL, Carlson JM, Wolinsky SM, Goedert JJ, Walker BD, Segal FP, Deeks SG, Haas DW, Migueles SA, Connors M, Michael N, Fellay J, Gostick E, Llewellyn-Lacey S, Price DA, Lafont BA, Pymm P, Saunders PM, Widjaja J, Wong SC, Vivian JP, Rossjohn J, Brooks AG, Carrington M. Martin MP, et al. Among authors: brooks ag. J Clin Invest. 2018 May 1;128(5):1903-1912. doi: 10.1172/JCI98463. Epub 2018 Apr 3. J Clin Invest. 2018. PMID: 29461980 Free PMC article. Clinical Trial.
The production, purification and crystallization of a soluble heterodimeric form of a highly selected T-cell receptor in its unliganded and liganded state.
Clements CS, Kjer-Nielsen L, MacDonald WA, Brooks AG, Purcell AW, McCluskey J, Rossjohn J. Clements CS, et al. Among authors: brooks ag. Acta Crystallogr D Biol Crystallogr. 2002 Dec;58(Pt 12):2131-4. doi: 10.1107/s0907444902015482. Epub 2002 Nov 23. Acta Crystallogr D Biol Crystallogr. 2002. PMID: 12454477
A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition.
Macdonald WA, Purcell AW, Mifsud NA, Ely LK, Williams DS, Chang L, Gorman JJ, Clements CS, Kjer-Nielsen L, Koelle DM, Burrows SR, Tait BD, Holdsworth R, Brooks AG, Lovrecz GO, Lu L, Rossjohn J, McCluskey J. Macdonald WA, et al. Among authors: brooks ag. J Exp Med. 2003 Sep 1;198(5):679-91. doi: 10.1084/jem.20030066. Epub 2003 Aug 25. J Exp Med. 2003. PMID: 12939341 Free PMC article.
Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion.
Zernich D, Purcell AW, Macdonald WA, Kjer-Nielsen L, Ely LK, Laham N, Crockford T, Mifsud NA, Bharadwaj M, Chang L, Tait BD, Holdsworth R, Brooks AG, Bottomley SP, Beddoe T, Peh CA, Rossjohn J, McCluskey J. Zernich D, et al. Among authors: brooks ag. J Exp Med. 2004 Jul 5;200(1):13-24. doi: 10.1084/jem.20031680. Epub 2004 Jun 28. J Exp Med. 2004. PMID: 15226359 Free PMC article.
The production and purification of the human T-cell receptors, the CD3epsilongamma and CD3epsilondelta heterodimers: complex formation and crystallization with OKT3, a therapeutic monoclonal antibody.
Dunstone MA, Kjer-Nielsen L, Kostenko L, Purcell AW, Brooks AG, Rossjohn J, McCluskey J. Dunstone MA, et al. Among authors: brooks ag. Acta Crystallogr D Biol Crystallogr. 2004 Aug;60(Pt 8):1425-8. doi: 10.1107/S0907444904012041. Epub 2004 Jul 21. Acta Crystallogr D Biol Crystallogr. 2004. PMID: 15272166
308 results