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Consecutive epigenetically-active agent combinations act in ID1-RUNX3-TET2 and HOXA pathways for Flt3ITD+ve AML.
Sayar H, Liu Y, Gao R, Zaid MA, Cripe LD, Weisenbach J, Sargent KJ, Nassiri M, Li L, Konig H, Suvannasankha A, Pan F, Shanmugam R, Goswami C, Kapur R, Xu M, Boswell HS. Sayar H, et al. Among authors: boswell hs. Oncotarget. 2017 Dec 25;9(5):5703-5715. doi: 10.18632/oncotarget.23655. eCollection 2018 Jan 19. Oncotarget. 2017. PMID: 29464028 Free PMC article.
A noncanonical Flt3ITD/NF-κB signaling pathway represses DAPK1 in acute myeloid leukemia.
Shanmugam R, Gade P, Wilson-Weekes A, Sayar H, Suvannasankha A, Goswami C, Li L, Gupta S, Cardoso AA, Baghdadi TA, Sargent KJ, Cripe LD, Kalvakolanu DV, Boswell HS. Shanmugam R, et al. Among authors: boswell hs. Clin Cancer Res. 2012 Jan 15;18(2):360-369. doi: 10.1158/1078-0432.CCR-10-3022. Epub 2011 Nov 17. Clin Cancer Res. 2012. PMID: 22096027 Free PMC article.
Antimyeloma effects of a sesquiterpene lactone parthenolide.
Suvannasankha A, Crean CD, Shanmugam R, Farag SS, Abonour R, Boswell HS, Nakshatri H. Suvannasankha A, et al. Among authors: boswell hs. Clin Cancer Res. 2008 Mar 15;14(6):1814-22. doi: 10.1158/1078-0432.CCR-07-1359. Clin Cancer Res. 2008. PMID: 18347184
Phosphatase PRL2 promotes AML1-ETO-induced acute myeloid leukemia.
Kobayashi M, Chen S, Bai Y, Yao C, Gao R, Sun XJ, Mu C, Twiggs TA, Yu ZH, Boswell HS, Yoder MC, Kapur R, Mulloy JC, Zhang ZY, Liu Y. Kobayashi M, et al. Among authors: boswell hs. Leukemia. 2017 Jun;31(6):1453-1457. doi: 10.1038/leu.2017.67. Epub 2017 Feb 21. Leukemia. 2017. PMID: 28220038 Free PMC article. No abstract available.
Mutant p53 enhances leukemia-initiating cell self-renewal to promote leukemia development.
Nabinger SC, Chen S, Gao R, Yao C, Kobayashi M, Vemula S, Fahey AC, Wang C, Daniels C, Boswell HS, Sandusky GE, Mayo LD, Kapur R, Liu Y. Nabinger SC, et al. Among authors: boswell hs. Leukemia. 2019 Jun;33(6):1535-1539. doi: 10.1038/s41375-019-0377-0. Epub 2019 Jan 23. Leukemia. 2019. PMID: 30675010 Free PMC article. No abstract available.
Mutant p53 drives clonal hematopoiesis through modulating epigenetic pathway.
Chen S, Wang Q, Yu H, Capitano ML, Vemula S, Nabinger SC, Gao R, Yao C, Kobayashi M, Geng Z, Fahey A, Henley D, Liu SZ, Barajas S, Cai W, Wolf ER, Ramdas B, Cai Z, Gao H, Luo N, Sun Y, Wong TN, Link DC, Liu Y, Boswell HS, Mayo LD, Huang G, Kapur R, Yoder MC, Broxmeyer HE, Gao Z, Liu Y. Chen S, et al. Among authors: boswell hs. Nat Commun. 2019 Dec 11;10(1):5649. doi: 10.1038/s41467-019-13542-2. Nat Commun. 2019. PMID: 31827082 Free PMC article.
Regulation of Stat5 by FAK and PAK1 in Oncogenic FLT3- and KIT-Driven Leukemogenesis.
Chatterjee A, Ghosh J, Ramdas B, Mali RS, Martin H, Kobayashi M, Vemula S, Canela VH, Waskow ER, Visconte V, Tiu RV, Smith CC, Shah N, Bunting KD, Boswell HS, Liu Y, Chan RJ, Kapur R. Chatterjee A, et al. Among authors: boswell hs. Cell Rep. 2014 Nov 20;9(4):1333-48. doi: 10.1016/j.celrep.2014.10.039. Epub 2014 Nov 13. Cell Rep. 2014. PMID: 25456130 Free PMC article.
74 results