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Hypercholesterolemia-Induced Loss of Flow-Induced Vasodilation and Lesion Formation in Apolipoprotein E-Deficient Mice Critically Depend on Inwardly Rectifying K+ Channels.
J Am Heart Assoc. 2018 Mar 3;7(5):e007430. doi: 10.1161/JAHA.117.007430.
J Am Heart Assoc. 2018.
PMID: 29502106
Free PMC article.
Impairment of Flow-Sensitive Inwardly Rectifying K+ Channels via Disruption of Glycocalyx Mediates Obesity-Induced Endothelial Dysfunction.
Fancher IS, Le Master E, Ahn SJ, Adamos C, Lee JC, Berdyshev E, Dull RO, Phillips SA, Levitan I.
Fancher IS, et al. Among authors: adamos c.
Arterioscler Thromb Vasc Biol. 2020 Sep;40(9):e240-e255. doi: 10.1161/ATVBAHA.120.314935. Epub 2020 Jul 23.
Arterioscler Thromb Vasc Biol. 2020.
PMID: 32698687
Free PMC article.
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Oxidized LDL signals through Rho-GTPase to induce endothelial cell stiffening and promote capillary formation.
Oh MJ, Zhang C, LeMaster E, Adamos C, Berdyshev E, Bogachkov Y, Kohler EE, Baruah J, Fang Y, Schraufnagel DE, Wary KK, Levitan I.
Oh MJ, et al. Among authors: adamos c.
J Lipid Res. 2016 May;57(5):791-808. doi: 10.1194/jlr.M062539. Epub 2016 Mar 17.
J Lipid Res. 2016.
PMID: 26989083
Free PMC article.
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oxLDL induces endothelial cell proliferation via Rho/ROCK/Akt/p27kip1 signaling: opposite effects of oxLDL and cholesterol loading.
Zhang C, Adamos C, Oh MJ, Baruah J, Ayee MAA, Mehta D, Wary KK, Levitan I.
Zhang C, et al. Among authors: adamos c.
Am J Physiol Cell Physiol. 2017 Sep 1;313(3):C340-C351. doi: 10.1152/ajpcell.00249.2016. Epub 2017 Jul 12.
Am J Physiol Cell Physiol. 2017.
PMID: 28701359
Free PMC article.
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