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Page 1
Whole-Genome Sequencing of Pharmacogenetic Drug Response in Racially Diverse Children with Asthma.
Mak ACY, White MJ, Eckalbar WL, Szpiech ZA, Oh SS, Pino-Yanes M, Hu D, Goddard P, Huntsman S, Galanter J, Wu AC, Himes BE, Germer S, Vogel JM, Bunting KL, Eng C, Salazar S, Keys KL, Liberto J, Nuckton TJ, Nguyen TA, Torgerson DG, Kwok PY, Levin AM, Celedón JC, Forno E, Hakonarson H, Sleiman PM, Dahlin A, Tantisira KG, Weiss ST, Serebrisky D, Brigino-Buenaventura E, Farber HJ, Meade K, Lenoir MA, Avila PC, Sen S, Thyne SM, Rodriguez-Cintron W, Winkler CA, Moreno-Estrada A, Sandoval K, Rodriguez-Santana JR, Kumar R, Williams LK, Ahituv N, Ziv E, Seibold MA, Darnell RB, Zaitlen N, Hernandez RD, Burchard EG; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium. Mak ACY, et al. Among authors: williams lk. Am J Respir Crit Care Med. 2018 Jun 15;197(12):1552-1564. doi: 10.1164/rccm.201712-2529OC. Am J Respir Crit Care Med. 2018. PMID: 29509491 Free PMC article.
Gene-environment interactions between CD14 C-260T and endotoxin exposure on Foxp3+ and Foxp3- CD4+ lymphocyte numbers and total serum IgE levels in early childhood.
Williams LK, Oliver J, Peterson EL, Bobbitt KR, McCabe MJ Jr, Smolarek D, Havstad SL, Wegienka G, Burchard EG, Ownby DR, Johnson CC. Williams LK, et al. Ann Allergy Asthma Immunol. 2008 Feb;100(2):128-36. doi: 10.1016/S1081-1206(10)60421-8. Ann Allergy Asthma Immunol. 2008. PMID: 18320914 Free PMC article.
An african-specific functional polymorphism in KCNMB1 shows sex-specific association with asthma severity.
Seibold MA, Wang B, Eng C, Kumar G, Beckman KB, Sen S, Choudhry S, Meade K, Lenoir M, Watson HG, Thyne S, Williams LK, Kumar R, Weiss KB, Grammer LC, Avila PC, Schleimer RP, Burchard EG, Brenner R. Seibold MA, et al. Among authors: williams lk. Hum Mol Genet. 2008 Sep 1;17(17):2681-90. doi: 10.1093/hmg/ddn168. Epub 2008 Jun 4. Hum Mol Genet. 2008. PMID: 18535015 Free PMC article.
Inhaled corticosteroids and augmented bronchodilator responsiveness in Latino and African American asthmatic patients.
Naqvi M, Tcheurekdjian H, DeBoard JA, Williams LK, Navarro D, Castro RA, Rodriguez-Santana JR, Chapela R, Watson HG, Meade K, Rodriguez-Cintron W, LeNoir M, Thyne SM, Avila PC, Choudhry S, Burchard EG. Naqvi M, et al. Among authors: williams lk. Ann Allergy Asthma Immunol. 2008 Jun;100(6):551-7. doi: 10.1016/S1081-1206(10)60055-5. Ann Allergy Asthma Immunol. 2008. PMID: 18592818
Differences in allergic sensitization by self-reported race and genetic ancestry.
Yang JJ, Burchard EG, Choudhry S, Johnson CC, Ownby DR, Favro D, Chen J, Akana M, Ha C, Kwok PY, Krajenta R, Havstad SL, Joseph CL, Seibold MA, Shriver MD, Williams LK. Yang JJ, et al. Among authors: williams lk. J Allergy Clin Immunol. 2008 Oct;122(4):820-827.e9. doi: 10.1016/j.jaci.2008.07.044. J Allergy Clin Immunol. 2008. PMID: 19014772 Free PMC article.
Genetic ancestry in lung-function predictions.
Kumar R, Seibold MA, Aldrich MC, Williams LK, Reiner AP, Colangelo L, Galanter J, Gignoux C, Hu D, Sen S, Choudhry S, Peterson EL, Rodriguez-Santana J, Rodriguez-Cintron W, Nalls MA, Leak TS, O'Meara E, Meibohm B, Kritchevsky SB, Li R, Harris TB, Nickerson DA, Fornage M, Enright P, Ziv E, Smith LJ, Liu K, Burchard EG. Kumar R, et al. Among authors: williams lk. N Engl J Med. 2010 Jul 22;363(4):321-30. doi: 10.1056/NEJMoa0907897. Epub 2010 Jul 7. N Engl J Med. 2010. PMID: 20647190 Free PMC article.
Dual-specificity phosphatase 1 as a pharmacogenetic modifier of inhaled steroid response among asthmatic patients.
Jin Y, Hu D, Peterson EL, Eng C, Levin AM, Wells K, Beckman K, Kumar R, Seibold MA, Karungi G, Zoratti A, Gaggin J, Campbell J, Galanter J, Chapela R, Rodríguez-Santana JR, Watson HG, Meade K, Lenoir M, Rodríguez-Cintrón W, Avila PC, Lanfear DE, Burchard EG, Williams LK. Jin Y, et al. Among authors: williams lk. J Allergy Clin Immunol. 2010 Sep;126(3):618-25.e1-2. doi: 10.1016/j.jaci.2010.06.007. Epub 2010 Jul 31. J Allergy Clin Immunol. 2010. PMID: 20673984 Free PMC article. Clinical Trial.
286 results