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Capture Hi-C identifies putative target genes at 33 breast cancer risk loci.
Baxter JS, Leavy OC, Dryden NH, Maguire S, Johnson N, Fedele V, Simigdala N, Martin LA, Andrews S, Wingett SW, Assiotis I, Fenwick K, Chauhan R, Rust AG, Orr N, Dudbridge F, Haider S, Fletcher O. Baxter JS, et al. Among authors: leavy oc. Nat Commun. 2018 Mar 12;9(1):1028. doi: 10.1038/s41467-018-03411-9. Nat Commun. 2018. PMID: 29531215 Free PMC article.
Replication of Newly Identified Genetic Associations Between Abdominal Aortic Aneurysm and SMYD2, LINC00540, PCIF1/MMP9/ZNF335, and ERG.
Tang W, Saratzis A, Pattee J, Smith J, Pankratz N, Leavy OC, Guan W, Dudbridge F, Pankow JS, Kitas GD, Lutsey PL, Bown MJ. Tang W, et al. Among authors: leavy oc. Eur J Vasc Endovasc Surg. 2020 Jan;59(1):92-97. doi: 10.1016/j.ejvs.2019.02.017. Epub 2019 Nov 1. Eur J Vasc Endovasc Surg. 2020. PMID: 31680049 Free PMC article.
Identifying high-confidence capture Hi-C interactions using CHiCANE.
Holgersen EM, Gillespie A, Leavy OC, Baxter JS, Zvereva A, Muirhead G, Johnson N, Sipos O, Dryden NH, Broome LR, Chen Y, Kozin I, Dudbridge F, Fletcher O, Haider S. Holgersen EM, et al. Among authors: leavy oc. Nat Protoc. 2021 Apr;16(4):2257-2285. doi: 10.1038/s41596-021-00498-1. Epub 2021 Apr 9. Nat Protoc. 2021. PMID: 33837305
The WID-BC-index identifies women with primary poor prognostic breast cancer based on DNA methylation in cervical samples.
Barrett JE, Herzog C, Jones A, Leavy OC, Evans I, Knapp S, Reisel D, Nazarenko T, Kim YN, Franchi D, Ryan A, Franks J, Bjørge L, Zikan M, Cibula D, Harbeck N, Colombo N, Dudbridge F, Jones L, Sundström K, Dillner J, Rådestad AF, Gemzell-Danielsson K, Pashayan N, Widschwendter M. Barrett JE, et al. Among authors: leavy oc. Nat Commun. 2022 Feb 1;13(1):449. doi: 10.1038/s41467-021-27918-w. Nat Commun. 2022. PMID: 35105882 Free PMC article.
The DNA methylome of cervical cells can predict the presence of ovarian cancer.
Barrett JE, Jones A, Evans I, Reisel D, Herzog C, Chindera K, Kristiansen M, Leavy OC, Manchanda R, Bjørge L, Zikan M, Cibula D, Widschwendter M. Barrett JE, et al. Among authors: leavy oc. Nat Commun. 2022 Feb 1;13(1):448. doi: 10.1038/s41467-021-26615-y. Nat Commun. 2022. PMID: 35105887 Free PMC article.
Genetically increased circulating FUT3 level leads to reduced risk of idiopathic pulmonary fibrosis: a Mendelian randomisation study.
Nakanishi T, Cerani A, Forgetta V, Zhou S, Allen RJ, Leavy OC, Koido M, Assayag D, Jenkins RG, Wain LV, Yang IV, Lathrop GM, Wolters PJ, Schwartz DA, Richards JB. Nakanishi T, et al. Among authors: leavy oc. Eur Respir J. 2022 Feb 10;59(2):2003979. doi: 10.1183/13993003.03979-2020. Print 2022 Feb. Eur Respir J. 2022. PMID: 34172473 Free PMC article.
Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study.
Evans RA, McAuley H, Harrison EM, Shikotra A, Singapuri A, Sereno M, Elneima O, Docherty AB, Lone NI, Leavy OC, Daines L, Baillie JK, Brown JS, Chalder T, De Soyza A, Diar Bakerly N, Easom N, Geddes JR, Greening NJ, Hart N, Heaney LG, Heller S, Howard L, Hurst JR, Jacob J, Jenkins RG, Jolley C, Kerr S, Kon OM, Lewis K, Lord JM, McCann GP, Neubauer S, Openshaw PJM, Parekh D, Pfeffer P, Rahman NM, Raman B, Richardson M, Rowland M, Semple MG, Shah AM, Singh SJ, Sheikh A, Thomas D, Toshner M, Chalmers JD, Ho LP, Horsley A, Marks M, Poinasamy K, Wain LV, Brightling CE; PHOSP-COVID Collaborative Group. Evans RA, et al. Among authors: leavy oc. Lancet Respir Med. 2021 Nov;9(11):1275-1287. doi: 10.1016/S2213-2600(21)00383-0. Epub 2021 Oct 7. Lancet Respir Med. 2021. PMID: 34627560 Free PMC article.
Longitudinal lung function and gas transfer in individuals with idiopathic pulmonary fibrosis: a genome-wide association study.
Allen RJ, Oldham JM, Jenkins DA, Leavy OC, Guillen-Guio B, Melbourne CA, Ma SF, Jou J, Kim JS; CleanUP-IPF Investigators of the Pulmonary Trials Cooperative; Fahy WA, Oballa E, Hubbard RB, Navaratnam V, Braybrooke R, Saini G, Roach KM, Tobin MD, Hirani N, Whyte MKB, Kaminski N, Zhang Y, Martinez FJ, Linderholm AL, Adegunsoye A, Strek ME, Maher TM, Molyneaux PL, Flores C, Noth I, Gisli Jenkins R, Wain LV. Allen RJ, et al. Among authors: leavy oc. Lancet Respir Med. 2023 Jan;11(1):65-73. doi: 10.1016/S2213-2600(22)00251-X. Epub 2022 Aug 16. Lancet Respir Med. 2023. PMID: 35985358 Free PMC article.
37 results