Molkentin JD - Search Results

1

Genetic Reduction in Left Ventricular Protein Kinase C-α and Adverse Ventricular Remodeling in Human Subjects.

Hu R, Morley MP, Brandimarto J, Tucker NR, Parsons VA, Zhao SD, Meder B, Katus HA, Rühle F, Stoll M, Villard E, Cambien F, Lin H, Smith NL, Felix JF, Vasan RS, van der Harst P, Newton-Cheh C, Li J, Kim CE, Hakonarson H, Hannenhalli S, Ashley EA, Moravec CS, Tang WHW, Maillet M, Molkentin JD, Ellinor PT, Margulies KB, Cappola TP. Hu R, et al. Among authors: molkentin jd. Circ Genom Precis Med. 2018 Mar;11(3):e001901. doi: 10.1161/CIRCGEN.117.001901. Circ Genom Precis Med. 2018. PMID: 29540468 Free PMC article.

2

Retinoic acid inhibits cardiac neural crest migration by blocking c-Jun N-terminal kinase activation.

Li J, Molkentin JD, Colbert MC. Li J, et al. Among authors: molkentin jd. Dev Biol. 2001 Apr 15;232(2):351-61. doi: 10.1006/dbio.2001.0203. Dev Biol. 2001. PMID: 11401397 Free article.

3

Cardiac-specific deletion of Gata4 reveals its requirement for hypertrophy, compensation, and myocyte viability.

Oka T, Maillet M, Watt AJ, Schwartz RJ, Aronow BJ, Duncan SA, Molkentin JD. Oka T, et al. Among authors: molkentin jd. Circ Res. 2006 Mar 31;98(6):837-45. doi: 10.1161/01.RES.0000215985.18538.c4. Epub 2006 Mar 2. Circ Res. 2006. PMID: 16514068

4

Pharmacological- and gene therapy-based inhibition of protein kinase Calpha/beta enhances cardiac contractility and attenuates heart failure.

Hambleton M, Hahn H, Pleger ST, Kuhn MC, Klevitsky R, Carr AN, Kimball TF, Hewett TE, Dorn GW 2nd, Koch WJ, Molkentin JD. Hambleton M, et al. Among authors: molkentin jd. Circulation. 2006 Aug 8;114(6):574-82. doi: 10.1161/CIRCULATIONAHA.105.592550. Epub 2006 Jul 31. Circulation. 2006. PMID: 16880328 Free PMC article.

5

Genetic manipulation of periostin expression reveals a role in cardiac hypertrophy and ventricular remodeling.

Oka T, Xu J, Kaiser RA, Melendez J, Hambleton M, Sargent MA, Lorts A, Brunskill EW, Dorn GW 2nd, Conway SJ, Aronow BJ, Robbins J, Molkentin JD. Oka T, et al. Among authors: molkentin jd. Circ Res. 2007 Aug 3;101(3):313-21. doi: 10.1161/CIRCRESAHA.107.149047. Epub 2007 Jun 14. Circ Res. 2007. PMID: 17569887 Free PMC article.

6

DUSP6 (MKP3) null mice show enhanced ERK1/2 phosphorylation at baseline and increased myocyte proliferation in the heart affecting disease susceptibility.

Maillet M, Purcell NH, Sargent MA, York AJ, Bueno OF, Molkentin JD. Maillet M, et al. Among authors: molkentin jd. J Biol Chem. 2008 Nov 7;283(45):31246-55. doi: 10.1074/jbc.M806085200. Epub 2008 Aug 27. J Biol Chem. 2008. PMID: 18753132 Free PMC article.

7

Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach.

Liu Q, Chen X, Macdonnell SM, Kranias EG, Lorenz JN, Leitges M, Houser SR, Molkentin JD. Liu Q, et al. Among authors: molkentin jd. Circ Res. 2009 Jul 17;105(2):194-200. doi: 10.1161/CIRCRESAHA.109.195313. Epub 2009 Jun 25. Circ Res. 2009. PMID: 19556521 Free PMC article.

8

Cdc42 is an antihypertrophic molecular switch in the mouse heart.

Maillet M, Lynch JM, Sanna B, York AJ, Zheng Y, Molkentin JD. Maillet M, et al. Among authors: molkentin jd. J Clin Invest. 2009 Oct;119(10):3079-88. doi: 10.1172/JCI37694. Epub 2009 Sep 8. J Clin Invest. 2009. PMID: 19741299 Free PMC article.

9

Genetic manipulation of dysferlin expression in skeletal muscle: novel insights into muscular dystrophy.

Millay DP, Maillet M, Roche JA, Sargent MA, McNally EM, Bloch RJ, Molkentin JD. Millay DP, et al. Among authors: molkentin jd. Am J Pathol. 2009 Nov;175(5):1817-23. doi: 10.2353/ajpath.2009.090107. Epub 2009 Oct 15. Am J Pathol. 2009. PMID: 19834057 Free PMC article.

10

Calcium influx is sufficient to induce muscular dystrophy through a TRPC-dependent mechanism.

Millay DP, Goonasekera SA, Sargent MA, Maillet M, Aronow BJ, Molkentin JD. Millay DP, et al. Among authors: molkentin jd. Proc Natl Acad Sci U S A. 2009 Nov 10;106(45):19023-8. doi: 10.1073/pnas.0906591106. Epub 2009 Oct 28. Proc Natl Acad Sci U S A. 2009. PMID: 19864620 Free PMC article.

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