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Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer.
Tria GS, Abrams T, Baird J, Burks HE, Firestone B, Gaither LA, Hamann LG, He G, Kirby CA, Kim S, Lombardo F, Macchi KJ, McDonnell DP, Mishina Y, Norris JD, Nunez J, Springer C, Sun Y, Thomsen NM, Wang C, Wang J, Yu B, Tiong-Yip CL, Peukert S. Tria GS, et al. Among authors: tiong yip cl. J Med Chem. 2018 Apr 12;61(7):2837-2864. doi: 10.1021/acs.jmedchem.7b01682. Epub 2018 Mar 22. J Med Chem. 2018. PMID: 29562737
Discovery of a potent respiratory syncytial virus RNA polymerase inhibitor.
Xiong H, Foulk M, Aschenbrenner L, Fan J, Tiong-Yip CL, Johnson KD, Moustakas D, Fleming PR, Brown DG, Zhang M, Ferguson D, Wu D, Yu Q. Xiong H, et al. Among authors: tiong yip cl. Bioorg Med Chem Lett. 2013 Dec 15;23(24):6789-93. doi: 10.1016/j.bmcl.2013.10.018. Epub 2013 Oct 16. Bioorg Med Chem Lett. 2013. PMID: 24211022
Characterization of a respiratory syncytial virus L protein inhibitor.
Tiong-Yip CL, Aschenbrenner L, Johnson KD, McLaughlin RE, Fan J, Challa S, Xiong H, Yu Q. Tiong-Yip CL, et al. Antimicrob Agents Chemother. 2014 Jul;58(7):3867-73. doi: 10.1128/AAC.02540-14. Epub 2014 Apr 28. Antimicrob Agents Chemother. 2014. PMID: 24777090 Free PMC article.
Mechanism of action for respiratory syncytial virus inhibitor RSV604.
Challa S, Scott AD, Yuzhakov O, Zhou Y, Tiong-Yip CL, Gao N, Thresher J, Yu Q. Challa S, et al. Among authors: tiong yip cl. Antimicrob Agents Chemother. 2015 Feb;59(2):1080-7. doi: 10.1128/AAC.04119-14. Epub 2014 Dec 1. Antimicrob Agents Chemother. 2015. PMID: 25451060 Free PMC article.