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Discovery of LSZ102, a Potent, Orally Bioavailable Selective Estrogen Receptor Degrader (SERD) for the Treatment of Estrogen Receptor Positive Breast Cancer.
J Med Chem. 2018 Apr 12;61(7):2837-2864. doi: 10.1021/acs.jmedchem.7b01682. Epub 2018 Mar 22.
J Med Chem. 2018.
PMID: 29562737
Tetrahydro anthranilic acid as a surrogate for anthranilic acid: application to the discovery of potent niacin receptor agonists.
Raghavan S, Tria GS, Shen HC, Ding FX, Taggart AK, Ren N, Wilsie LC, Krsmanovic ML, Holt TG, Wolff MS, Waters MG, Hammond ML, Tata JR, Colletti SL.
Raghavan S, et al. Among authors: tria gs.
Bioorg Med Chem Lett. 2008 Jun 1;18(11):3163-7. doi: 10.1016/j.bmcl.2008.04.071. Epub 2008 May 1.
Bioorg Med Chem Lett. 2008.
PMID: 18477506
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Design, synthesis, and biological evaluation of platensimycin analogues with varying degrees of molecular complexity.
Nicolaou KC, Stepan AF, Lister T, Li A, Montero A, Tria GS, Turner CI, Tang Y, Wang J, Denton RM, Edmonds DJ.
Nicolaou KC, et al. Among authors: tria gs.
J Am Chem Soc. 2008 Oct 1;130(39):13110-9. doi: 10.1021/ja8044376. Epub 2008 Sep 5.
J Am Chem Soc. 2008.
PMID: 18771264
Free PMC article.
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Asymmetric total syntheses of platensimycin.
Nicolaou KC, Edmonds DJ, Li A, Tria GS.
Nicolaou KC, et al. Among authors: tria gs.
Angew Chem Int Ed Engl. 2007;46(21):3942-5. doi: 10.1002/anie.200700586.
Angew Chem Int Ed Engl. 2007.
PMID: 17444571
No abstract available.
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Total synthesis of platencin.
Nicolaou KC, Tria GS, Edmonds DJ.
Nicolaou KC, et al. Among authors: tria gs.
Angew Chem Int Ed Engl. 2008;47(9):1780-3. doi: 10.1002/anie.200800066.
Angew Chem Int Ed Engl. 2008.
PMID: 18246566
No abstract available.
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Total syntheses of (+/-)-platencin and (-)-platencin.
Nicolaou KC, Tria GS, Edmonds DJ, Kar M.
Nicolaou KC, et al. Among authors: tria gs.
J Am Chem Soc. 2009 Nov 4;131(43):15909-17. doi: 10.1021/ja906801g.
J Am Chem Soc. 2009.
PMID: 19824676
Free PMC article.
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Total synthesis of platensimycin and related natural products.
Nicolaou KC, Li A, Edmonds DJ, Tria GS, Ellery SP.
Nicolaou KC, et al. Among authors: tria gs.
J Am Chem Soc. 2009 Nov 25;131(46):16905-18. doi: 10.1021/ja9068003.
J Am Chem Soc. 2009.
PMID: 19874023
Free PMC article.
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Activation of human STING by a molecular glue-like compound.
Li J, Canham SM, Wu H, Henault M, Chen L, Liu G, Chen Y, Yu G, Miller HR, Hornak V, Brittain SM, Michaud GA, Tutter A, Broom W, Digan ME, McWhirter SM, Sivick KE, Pham HT, Chen CH, Tria GS, McKenna JM, Schirle M, Mao X, Nicholson TB, Wang Y, Jenkins JL, Jain RK, Tallarico JA, Patel SJ, Zheng L, Ross NT, Cho CY, Zhang X, Bai XC, Feng Y.
Li J, et al. Among authors: tria gs.
Nat Chem Biol. 2024 Mar;20(3):365-372. doi: 10.1038/s41589-023-01434-y. Epub 2023 Oct 12.
Nat Chem Biol. 2024.
PMID: 37828400
Free PMC article.
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