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Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types.
Finucane HK, Reshef YA, Anttila V, Slowikowski K, Gusev A, Byrnes A, Gazal S, Loh PR, Lareau C, Shoresh N, Genovese G, Saunders A, Macosko E, Pollack S; Brainstorm Consortium; Perry JRB, Buenrostro JD, Bernstein BE, Raychaudhuri S, McCarroll S, Neale BM, Price AL. Finucane HK, et al. Among authors: lareau c. Nat Genet. 2018 Apr;50(4):621-629. doi: 10.1038/s41588-018-0081-4. Epub 2018 Apr 9. Nat Genet. 2018. PMID: 29632380 Free PMC article.
FOXO1 is a master regulator of CAR T memory programming.
Doan A, Mueller KP, Chen A, Rouin GT, Daniel B, Lattin J, Chen Y, Mozarsky B, Markovska M, Arias-Umana J, Hapke R, Jung I, Xu P, Klysz D, Bashti M, Quinn PJ, Sandor K, Zhang W, Hall J, Lareau C, Grupp SA, Fraietta JA, Sotillo E, Satpathy AT, Mackall CL, Weber EW. Doan A, et al. Among authors: lareau c. Res Sq [Preprint]. 2023 Nov 7:rs.3.rs-2802998. doi: 10.21203/rs.3.rs-2802998/v1. Res Sq. 2023. PMID: 37986944 Free PMC article. Updated. Preprint.
Transcript-specific enrichment enables profiling rare cell states via scRNA-seq.
Abay T, Stickels RR, Takizawa MT, Nalbant BN, Hsieh YH, Hwang S, Snopkowski C, Yu KKH, Abou-Mrad Z, Tabar V, Ludwig LS, Chaligné R, Satpathy AT, Lareau CA. Abay T, et al. Among authors: lareau ca. bioRxiv [Preprint]. 2024 Mar 27:2024.03.27.587039. doi: 10.1101/2024.03.27.587039. bioRxiv. 2024. PMID: 38586040 Free PMC article. Preprint.
A B Cell Regulome Links Notch to Downstream Oncogenic Pathways in Small B Cell Lymphomas.
Ryan RJH, Petrovic J, Rausch DM, Zhou Y, Lareau CA, Kluk MJ, Christie AL, Lee WY, Tarjan DR, Guo B, Donohue LKH, Gillespie SM, Nardi V, Hochberg EP, Blacklow SC, Weinstock DM, Faryabi RB, Bernstein BE, Aster JC, Pear WS. Ryan RJH, et al. Among authors: lareau ca. Cell Rep. 2017 Oct 17;21(3):784-797. doi: 10.1016/j.celrep.2017.09.066. Cell Rep. 2017. PMID: 29045844 Free PMC article.
Transcript-indexed ATAC-seq for precision immune profiling.
Satpathy AT, Saligrama N, Buenrostro JD, Wei Y, Wu B, Rubin AJ, Granja JM, Lareau CA, Li R, Qi Y, Parker KR, Mumbach MR, Serratelli WS, Gennert DG, Schep AN, Corces MR, Khodadoust MS, Kim YH, Khavari PA, Greenleaf WJ, Davis MM, Chang HY. Satpathy AT, et al. Nat Med. 2018 May;24(5):580-590. doi: 10.1038/s41591-018-0008-8. Epub 2018 Apr 23. Nat Med. 2018. PMID: 29686426 Free PMC article.
The cis-Regulatory Atlas of the Mouse Immune System.
Yoshida H, Lareau CA, Ramirez RN, Rose SA, Maier B, Wroblewska A, Desland F, Chudnovskiy A, Mortha A, Dominguez C, Tellier J, Kim E, Dwyer D, Shinton S, Nabekura T, Qi Y, Yu B, Robinette M, Kim KW, Wagers A, Rhoads A, Nutt SL, Brown BD, Mostafavi S, Buenrostro JD, Benoist C; Immunological Genome Project. Yoshida H, et al. Among authors: lareau ca. Cell. 2019 Feb 7;176(4):897-912.e20. doi: 10.1016/j.cell.2018.12.036. Epub 2019 Jan 24. Cell. 2019. PMID: 30686579 Free PMC article.
Lineage Tracing in Humans Enabled by Mitochondrial Mutations and Single-Cell Genomics.
Ludwig LS, Lareau CA, Ulirsch JC, Christian E, Muus C, Li LH, Pelka K, Ge W, Oren Y, Brack A, Law T, Rodman C, Chen JH, Boland GM, Hacohen N, Rozenblatt-Rosen O, Aryee MJ, Buenrostro JD, Regev A, Sankaran VG. Ludwig LS, et al. Among authors: lareau ca. Cell. 2019 Mar 7;176(6):1325-1339.e22. doi: 10.1016/j.cell.2019.01.022. Epub 2019 Feb 28. Cell. 2019. PMID: 30827679 Free PMC article.
133 results