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Page 1
Faulty neuronal determination and cell polarization are reverted by modulating HD early phenotypes.
Conforti P, Besusso D, Bocchi VD, Faedo A, Cesana E, Rossetti G, Ranzani V, Svendsen CN, Thompson LM, Toselli M, Biella G, Pagani M, Cattaneo E. Conforti P, et al. Among authors: bocchi vd. Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E762-E771. doi: 10.1073/pnas.1715865115. Epub 2018 Jan 8. Proc Natl Acad Sci U S A. 2018. PMID: 29311338 Free PMC article.
Stem Cell-Derived Human Striatal Progenitors Innervate Striatal Targets and Alleviate Sensorimotor Deficit in a Rat Model of Huntington Disease.
Besusso D, Schellino R, Boido M, Belloli S, Parolisi R, Conforti P, Faedo A, Cernigoj M, Campus I, Laporta A, Bocchi VD, Murtaj V, Parmar M, Spaiardi P, Talpo F, Maniezzi C, Toselli MG, Biella G, Moresco RM, Vercelli A, Buffo A, Cattaneo E. Besusso D, et al. Among authors: bocchi vd. Stem Cell Reports. 2020 May 12;14(5):876-891. doi: 10.1016/j.stemcr.2020.03.018. Epub 2020 Apr 16. Stem Cell Reports. 2020. PMID: 32302555 Free PMC article.
Striatal infusion of cholesterol promotes dose-dependent behavioral benefits and exerts disease-modifying effects in Huntington's disease mice.
Birolini G, Valenza M, Di Paolo E, Vezzoli E, Talpo F, Maniezzi C, Caccia C, Leoni V, Taroni F, Bocchi VD, Conforti P, Sogne E, Petricca L, Cariulo C, Verani M, Caricasole A, Falqui A, Biella G, Cattaneo E. Birolini G, et al. Among authors: bocchi vd. EMBO Mol Med. 2020 Oct 7;12(10):e12519. doi: 10.15252/emmm.202012519. Epub 2020 Sep 22. EMBO Mol Med. 2020. PMID: 32959531 Free PMC article.
The coding and long noncoding single-cell atlas of the developing human fetal striatum.
Bocchi VD, Conforti P, Vezzoli E, Besusso D, Cappadona C, Lischetti T, Galimberti M, Ranzani V, Bonnal RJP, De Simone M, Rossetti G, He X, Kamimoto K, Espuny-Camacho I, Faedo A, Gervasoni F, Vuono R, Morris SA, Chen J, Felsenfeld D, Pavesi G, Barker RA, Pagani M, Cattaneo E. Bocchi VD, et al. Science. 2021 May 7;372(6542):eabf5759. doi: 10.1126/science.abf5759. Science. 2021. PMID: 33958447 Free article.
The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities.
Iennaco R, Formenti G, Trovesi C, Rossi RL, Zuccato C, Lischetti T, Bocchi VD, Scolz A, Martínez-Labarga C, Rickards O, Pacifico M, Crottini A, Møller AP, Chen RZ, Vogt TF, Pavesi G, Horner DS, Saino N, Cattaneo E. Iennaco R, et al. Among authors: bocchi vd. Cell Death Differ. 2022 Feb;29(2):293-305. doi: 10.1038/s41418-021-00914-9. Epub 2022 Jan 1. Cell Death Differ. 2022. PMID: 34974533 Free PMC article.
Modeling human telencephalic development and autism-associated SHANK3 deficiency using organoids generated from single neural rosettes.
Wang Y, Chiola S, Yang G, Russell C, Armstrong CJ, Wu Y, Spampanato J, Tarboton P, Ullah HMA, Edgar NU, Chang AN, Harmin DA, Bocchi VD, Vezzoli E, Besusso D, Cui J, Cattaneo E, Kubanek J, Shcheglovitov A. Wang Y, et al. Among authors: bocchi vd. Nat Commun. 2022 Oct 6;13(1):5688. doi: 10.1038/s41467-022-33364-z. Nat Commun. 2022. PMID: 36202854 Free PMC article.
In vitro-derived medium spiny neurons recapitulate human striatal development and complexity at single-cell resolution.
Conforti P, Bocchi VD, Campus I, Scaramuzza L, Galimberti M, Lischetti T, Talpo F, Pedrazzoli M, Murgia A, Ferrari I, Cordiglieri C, Fasciani A, Arenas E, Felsenfeld D, Biella G, Besusso D, Cattaneo E. Conforti P, et al. Among authors: bocchi vd. Cell Rep Methods. 2022 Dec 19;2(12):100367. doi: 10.1016/j.crmeth.2022.100367. eCollection 2022 Dec 19. Cell Rep Methods. 2022. PMID: 36590694 Free PMC article.
Generation of human cerebral organoids with a structured outer subventricular zone.
Walsh RM, Luongo R, Giacomelli E, Ciceri G, Rittenhouse C, Verrillo A, Galimberti M, Bocchi VD, Wu Y, Xu N, Mosole S, Muller J, Vezzoli E, Jungverdorben J, Zhou T, Barker RA, Cattaneo E, Studer L, Baggiolini A. Walsh RM, et al. Among authors: bocchi vd. Cell Rep. 2024 Apr 23;43(4):114031. doi: 10.1016/j.celrep.2024.114031. Epub 2024 Apr 6. Cell Rep. 2024. PMID: 38583153 Free article.