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The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities.
Iennaco R, Formenti G, Trovesi C, Rossi RL, Zuccato C, Lischetti T, Bocchi VD, Scolz A, Martínez-Labarga C, Rickards O, Pacifico M, Crottini A, Møller AP, Chen RZ, Vogt TF, Pavesi G, Horner DS, Saino N, Cattaneo E. Iennaco R, et al. Cell Death Differ. 2022 Feb;29(2):293-305. doi: 10.1038/s41418-021-00914-9. Epub 2022 Jan 1. Cell Death Differ. 2022. PMID: 34974533 Free PMC article.
Human Cortical Organoids Expose a Differential Function of GSK3 on Cortical Neurogenesis.
López-Tobón A, Villa CE, Cheroni C, Trattaro S, Caporale N, Conforti P, Iennaco R, Lachgar M, Rigoli MT, Marcó de la Cruz B, Lo Riso P, Tenderini E, Troglio F, De Simone M, Liste-Noya I, Macino G, Pagani M, Cattaneo E, Testa G. López-Tobón A, et al. Among authors: iennaco r. Stem Cell Reports. 2019 Nov 12;13(5):847-861. doi: 10.1016/j.stemcr.2019.09.005. Epub 2019 Oct 10. Stem Cell Reports. 2019. PMID: 31607568 Free PMC article.
Huntingtin gene CAG repeat size affects autism risk: Family-based and case-control association study.
Piras IS, Picinelli C, Iennaco R, Baccarin M, Castronovo P, Tomaiuolo P, Cucinotta F, Ricciardello A, Turriziani L, Nanetti L, Mariotti C, Gellera C, Lintas C, Sacco R, Zuccato C, Cattaneo E, Persico AM. Piras IS, et al. Among authors: iennaco r. Am J Med Genet B Neuropsychiatr Genet. 2020 Sep;183(6):341-351. doi: 10.1002/ajmg.b.32806. Epub 2020 Jul 11. Am J Med Genet B Neuropsychiatr Genet. 2020. PMID: 32652810