Leeder JS - Search Results

1

Age- and Genotype-Dependent Variability in the Protein Abundance and Activity of Six Major Uridine Diphosphate-Glucuronosyltransferases in Human Liver.

Bhatt DK, Mehrotra A, Gaedigk A, Chapa R, Basit A, Zhang H, Choudhari P, Boberg M, Pearce RE, Gaedigk R, Broeckel U, Leeder JS, Prasad B. Bhatt DK, et al. Among authors: leeder js. Clin Pharmacol Ther. 2019 Jan;105(1):131-141. doi: 10.1002/cpt.1109. Epub 2018 Jul 12. Clin Pharmacol Ther. 2019. PMID: 29737521 Free PMC article.

2

Epitope mapping studies with human anti-cytochrome P450 3A antibodies.

Leeder JS, Gaedigk A, Lu X, Cook VA. Leeder JS, et al. Mol Pharmacol. 1996 Feb;49(2):234-43. Mol Pharmacol. 1996. PMID: 8632755

3

Tissue-specific expression and alternative splicing of human microsomal epoxide hydrolase.

Gaedigk A, Leeder JS, Grant DM. Gaedigk A, et al. Among authors: leeder js. DNA Cell Biol. 1997 Nov;16(11):1257-66. doi: 10.1089/dna.1997.16.1257. DNA Cell Biol. 1997. PMID: 9406998

4

Chiral phase analysis of warfarin enantiomers in patient plasma in relation to CYP2C9 genotype.

Henne KR, Gaedigk A, Gupta G, Leeder JS, Rettie AE. Henne KR, et al. Among authors: leeder js. J Chromatogr B Biomed Sci Appl. 1998 Jun 12;710(1-2):143-8. doi: 10.1016/s0378-4347(98)00099-1. J Chromatogr B Biomed Sci Appl. 1998. PMID: 9686881

5

NAD(P)H:quinone oxidoreductase: polymorphisms and allele frequencies in Caucasian, Chinese and Canadian Native Indian and Inuit populations.

Gaedigk A, Tyndale RF, Jurima-Romet M, Sellers EM, Grant DM, Leeder JS. Gaedigk A, et al. Among authors: leeder js. Pharmacogenetics. 1998 Aug;8(4):305-13. doi: 10.1097/00008571-199808000-00004. Pharmacogenetics. 1998. PMID: 9731717

6

Dose dependency of dextromethorphan for cytochrome P450 2D6 (CYP2D6) phenotyping.

Streetman DS, Ellis RE, Nafziger AN, Leeder JS, Gaedigk A, Gotschall R, Kearns GL, Bertino JS Jr. Streetman DS, et al. Among authors: leeder js. Clin Pharmacol Ther. 1999 Nov;66(5):535-41. doi: 10.1016/S0009-9236(99)70018-4. Clin Pharmacol Ther. 1999. PMID: 10579482 Clinical Trial.

7

Optimization of cytochrome P4502D6 (CYP2D6) phenotype assignment using a genotyping algorithm based on allele frequency data.

Gaedigk A, Gotschall RR, Forbes NS, Simon SD, Kearns GL, Leeder JS. Gaedigk A, et al. Among authors: leeder js. Pharmacogenetics. 1999 Dec;9(6):669-82. doi: 10.1097/01213011-199912000-00002. Pharmacogenetics. 1999. PMID: 10634130

8

Combined phenotypic assessment of CYP1A2, CYP2C19, CYP2D6, CYP3A, N-acetyltransferase-2, and xanthine oxidase with the "Cooperstown cocktail".

Streetman DS, Bleakley JF, Kim JS, Nafziger AN, Leeder JS, Gaedigk A, Gotschall R, Kearns GL, Bertino JS Jr. Streetman DS, et al. Among authors: leeder js. Clin Pharmacol Ther. 2000 Oct;68(4):375-83. doi: 10.1067/mcp.2000.109519. Clin Pharmacol Ther. 2000. PMID: 11061577

9

Cytochrome P4502C9 (CYP2C9) allele frequencies in Canadian Native Indian and Inuit populations.

Gaedigk A, Casley WL, Tyndale RF, Sellers EM, Jurima-Romet M, Leeder JS. Gaedigk A, et al. Among authors: leeder js. Can J Physiol Pharmacol. 2001 Oct;79(10):841-7. Can J Physiol Pharmacol. 2001. PMID: 11697742

10

Cytochrome P450 Involvement in the biotransformation of cisapride and racemic norcisapride in vitro: differential activity of individual human CYP3A isoforms.

Pearce RE, Gotschall RR, Kearns GL, Leeder JS. Pearce RE, et al. Among authors: leeder js. Drug Metab Dispos. 2001 Dec;29(12):1548-54. Drug Metab Dispos. 2001. PMID: 11717173

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