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CRISPR/Cas9 editing in human pluripotent stem cell-cardiomyocytes highlights arrhythmias, hypocontractility, and energy depletion as potential therapeutic targets for hypertrophic cardiomyopathy.
Mosqueira D, Mannhardt I, Bhagwan JR, Lis-Slimak K, Katili P, Scott E, Hassan M, Prondzynski M, Harmer SC, Tinker A, Smith JGW, Carrier L, Williams PM, Gaffney D, Eschenhagen T, Hansen A, Denning C. Mosqueira D, et al. Among authors: harmer sc. Eur Heart J. 2018 Nov 14;39(43):3879-3892. doi: 10.1093/eurheartj/ehy249. Eur Heart J. 2018. PMID: 29741611 Free PMC article.
Mechanisms of disease pathogenesis in long QT syndrome type 5.
Harmer SC, Wilson AJ, Aldridge R, Tinker A. Harmer SC, et al. Am J Physiol Cell Physiol. 2010 Feb;298(2):C263-73. doi: 10.1152/ajpcell.00308.2009. Epub 2009 Nov 11. Am J Physiol Cell Physiol. 2010. PMID: 19907016 Free PMC article.
37 results