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A New Strategy to Control and Eradicate "Undruggable" Oncogenic K-RAS-Driven Pancreatic Cancer: Molecular Insights and Core Principles Learned from Developmental and Evolutionary Biology.
Van Sciver RE, Lee MP, Lee CD, Lafever AC, Svyatova E, Kanda K, Colliver AL, Siewertsz van Reesema LL, Tang-Tan AM, Zheleva V, Bwayi MN, Bian M, Schmidt RL, Matrisian LM, Petersen GM, Tang AH. Van Sciver RE, et al. Among authors: lee cd, lee mp. Cancers (Basel). 2018 May 14;10(5):142. doi: 10.3390/cancers10050142. Cancers (Basel). 2018. PMID: 29757973 Free PMC article. Review.
Unmet Clinical Need: Developing Prognostic Biomarkers and Precision Medicine to Forecast Early Tumor Relapse, Detect Chemo-Resistance and Improve Overall Survival in High-Risk Breast Cancer.
Gupta G, Lee CD, Guye ML, Van Sciver RE, Lee MP, Lafever AC, Pang A, Tang-Tan AM, Winston JS, Samli B, Jansen RJ, Hoefer RA, Tang AH. Gupta G, et al. Among authors: lee cd, lee mp. Ann Breast Cancer Ther. 2020 May 2;4(1):48-57. doi: 10.36959/739/525. Ann Breast Cancer Ther. 2020. PMID: 32542231 Free PMC article.
Affinity gaps among B cells in germinal centers drive the selection of MPER precursors.
Ray R, Schiffner T, Wang X, Yan Y, Rantalainen K, Lee CD, Parikh S, Reyes RA, Dale GA, Lin YC, Pecetta S, Giguere S, Swanson O, Kratochvil S, Melzi E, Phung I, Madungwe L, Kalyuzhniy O, Warner J, Weldon SR, Tingle R, Lamperti E, Kirsch KH, Phelps N, Georgeson E, Adachi Y, Kubitz M, Nair U, Crotty S, Wilson IA, Schief WR, Batista FD. Ray R, et al. Among authors: lee cd. Nat Immunol. 2024 May 30. doi: 10.1038/s41590-024-01844-7. Online ahead of print. Nat Immunol. 2024. PMID: 38816616
Vaccination induces broadly neutralizing antibody precursors to HIV gp41.
Schiffner T, Phung I, Ray R, Irimia A, Tian M, Swanson O, Lee JH, Lee CD, Marina-Zárate E, Cho SY, Huang J, Ozorowski G, Skog PD, Serra AM, Rantalainen K, Allen JD, Baboo S, Rodriguez OL, Himansu S, Zhou J, Hurtado J, Flynn CT, McKenney K, Havenar-Daughton C, Saha S, Shields K, Schulze S, Smith ML, Liang CH, Toy L, Pecetta S, Lin YC, Willis JR, Sesterhenn F, Kulp DW, Hu X, Cottrell CA, Zhou X, Ruiz J, Wang X, Nair U, Kirsch KH, Cheng HL, Davis J, Kalyuzhniy O, Liguori A, Diedrich JK, Ngo JT, Lewis V, Phelps N, Tingle RD, Spencer S, Georgeson E, Adachi Y, Kubitz M, Eskandarzadeh S, Elsliger MA, Amara RR, Landais E, Briney B, Burton DR, Carnathan DG, Silvestri G, Watson CT, Yates JR 3rd, Paulson JC, Crispin M, Grigoryan G, Ward AB, Sok D, Alt FW, Wilson IA, Batista FD, Crotty S, Schief WR. Schiffner T, et al. Among authors: lee cd. Nat Immunol. 2024 May 30. doi: 10.1038/s41590-024-01833-w. Online ahead of print. Nat Immunol. 2024. PMID: 38816615
A conserved switch controls virulence, sporulation, and motility in C. difficile.
DiCandia MA, Edwards AN, Alcaraz YB, Monteiro MP, Lee CD, Vargas Cuebas G, Bagchi P, McBride SM. DiCandia MA, et al. Among authors: lee cd. PLoS Pathog. 2024 May 13;20(5):e1012224. doi: 10.1371/journal.ppat.1012224. eCollection 2024 May. PLoS Pathog. 2024. PMID: 38739653 Free PMC article.
254 results