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An integrated platform approach enables discovery of potent, selective and ligand-competitive cyclic peptides targeting the GIP receptor.
Bhushan B, Granata D, Kaas CS, Kasimova MA, Ren Q, Cramer CN, White MD, Hansen AMK, Fledelius C, Invernizzi G, Deibler K, Coleman OD, Zhao X, Qu X, Liu H, Zurmühl SS, Kodra JT, Kawamura A, Münzel M. Bhushan B, et al. Among authors: kaas cs. Chem Sci. 2022 Feb 24;13(11):3256-3262. doi: 10.1039/d1sc06844j. eCollection 2022 Mar 16. Chem Sci. 2022. PMID: 35414877 Free PMC article.
Identification and engineering of potent cyclic peptides with selective or promiscuous binding through biochemical profiling and bioinformatic data analysis.
Smith TP, Bhushan B, Granata D, Kaas CS, Andersen B, Decoene KW, Ren Q, Liu H, Qu X, Yang Y, Pan J, Chen Q, Münzel M, Kawamura A. Smith TP, et al. Among authors: kaas cs. RSC Chem Biol. 2023 Nov 14;5(1):12-18. doi: 10.1039/d3cb00168g. eCollection 2024 Jan 3. RSC Chem Biol. 2023. PMID: 38179194 Free PMC article.
11 results