Rader C - Search Results

1

Potent and selective antitumor activity of a T cell-engaging bispecific antibody targeting a membrane-proximal epitope of ROR1.

Qi J, Li X, Peng H, Cook EM, Dadashian EL, Wiestner A, Park H, Rader C. Qi J, et al. Among authors: rader c. Proc Natl Acad Sci U S A. 2018 Jun 12;115(24):E5467-E5476. doi: 10.1073/pnas.1719905115. Epub 2018 May 29. Proc Natl Acad Sci U S A. 2018. PMID: 29844189 Free PMC article.

2

Unique cell surface expression of receptor tyrosine kinase ROR1 in human B-cell chronic lymphocytic leukemia.

Baskar S, Kwong KY, Hofer T, Levy JM, Kennedy MG, Lee E, Staudt LM, Wilson WH, Wiestner A, Rader C. Baskar S, et al. Among authors: rader c. Clin Cancer Res. 2008 Jan 15;14(2):396-404. doi: 10.1158/1078-0432.CCR-07-1823. Clin Cancer Res. 2008. PMID: 18223214

3

Bortezomib resistance in mantle cell lymphoma is associated with plasmacytic differentiation.

Pérez-Galán P, Mora-Jensen H, Weniger MA, Shaffer AL 3rd, Rizzatti EG, Chapman CM, Mo CC, Stennett LS, Rader C, Liu P, Raghavachari N, Stetler-Stevenson M, Yuan C, Pittaluga S, Maric I, Dunleavy KM, Wilson WH, Staudt LM, Wiestner A. Pérez-Galán P, et al. Among authors: rader c. Blood. 2011 Jan 13;117(2):542-52. doi: 10.1182/blood-2010-02-269514. Epub 2010 Oct 18. Blood. 2011. PMID: 20956803 Free PMC article. Clinical Trial.

4

Therapeutic potential and challenges of targeting receptor tyrosine kinase ROR1 with monoclonal antibodies in B-cell malignancies.

Yang J, Baskar S, Kwong KY, Kennedy MG, Wiestner A, Rader C. Yang J, et al. Among authors: rader c. PLoS One. 2011;6(6):e21018. doi: 10.1371/journal.pone.0021018. Epub 2011 Jun 15. PLoS One. 2011. PMID: 21698301 Free PMC article.

5

Targeting malignant B cells with an immunotoxin against ROR1.

Baskar S, Wiestner A, Wilson WH, Pastan I, Rader C. Baskar S, et al. Among authors: rader c. MAbs. 2012 May-Jun;4(3):349-61. doi: 10.4161/mabs.19870. Epub 2012 Apr 26. MAbs. 2012. PMID: 22531447 Free PMC article.

6

Chemically programmed bispecific antibodies that recruit and activate T cells.

Cui H, Thomas JD, Burke TR Jr, Rader C. Cui H, et al. Among authors: rader c. J Biol Chem. 2012 Aug 17;287(34):28206-14. doi: 10.1074/jbc.M112.384594. Epub 2012 Jul 3. J Biol Chem. 2012. PMID: 22761439 Free PMC article.

7

Restricted cell surface expression of receptor tyrosine kinase ROR1 in pediatric B-lineage acute lymphoblastic leukemia suggests targetability with therapeutic monoclonal antibodies.

Dave H, Anver MR, Butcher DO, Brown P, Khan J, Wayne AS, Baskar S, Rader C. Dave H, et al. Among authors: rader c. PLoS One. 2012;7(12):e52655. doi: 10.1371/journal.pone.0052655. Epub 2012 Dec 20. PLoS One. 2012. PMID: 23285131 Free PMC article.

8

Antibody conjugation via one and two C-terminal selenocysteines.

Li X, Yang J, Rader C. Li X, et al. Among authors: rader c. Methods. 2014 Jan 1;65(1):133-8. doi: 10.1016/j.ymeth.2013.05.023. Epub 2013 Jun 10. Methods. 2014. PMID: 23756202 Free PMC article.

9

Tumor antigen ROR1 targeted drug delivery mediated selective leukemic but not normal B-cell cytotoxicity in chronic lymphocytic leukemia.

Mani R, Mao Y, Frissora FW, Chiang CL, Wang J, Zhao Y, Wu Y, Yu B, Yan R, Mo X, Yu L, Flynn J, Jones J, Andritsos L, Baskar S, Rader C, Phelps MA, Chen CS, Lee RJ, Byrd JC, Lee LJ, Muthusamy N. Mani R, et al. Among authors: rader c. Leukemia. 2015 Feb;29(2):346-55. doi: 10.1038/leu.2014.199. Epub 2014 Jun 20. Leukemia. 2015. PMID: 24947019 Free PMC article.

10

Improving the serum stability of site-specific antibody conjugates with sulfone linkers.

Patterson JT, Asano S, Li X, Rader C, Barbas CF 3rd. Patterson JT, et al. Among authors: rader c. Bioconjug Chem. 2014 Aug 20;25(8):1402-7. doi: 10.1021/bc500276m. Epub 2014 Aug 6. Bioconjug Chem. 2014. PMID: 25099687 Free PMC article.

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