Herold MJ - Search Results

1

DNA repair processes are critical mediators of p53-dependent tumor suppression.

Janic A, Valente LJ, Wakefield MJ, Di Stefano L, Milla L, Wilcox S, Yang H, Tai L, Vandenberg CJ, Kueh AJ, Mizutani S, Brennan MS, Schenk RL, Lindqvist LM, Papenfuss AT, O'Connor L, Strasser A, Herold MJ. Janic A, et al. Among authors: herold mj. Nat Med. 2018 Jul;24(7):947-953. doi: 10.1038/s41591-018-0043-5. Epub 2018 Jun 11. Nat Med. 2018. PMID: 29892060

2

Maximal killing of lymphoma cells by DNA damage-inducing therapy requires not only the p53 targets Puma and Noxa, but also Bim.

Happo L, Cragg MS, Phipson B, Haga JM, Jansen ES, Herold MJ, Dewson G, Michalak EM, Vandenberg CJ, Smyth GK, Strasser A, Cory S, Scott CL. Happo L, et al. Among authors: herold mj. Blood. 2010 Dec 9;116(24):5256-67. doi: 10.1182/blood-2010-04-280818. Epub 2010 Sep 9. Blood. 2010. PMID: 20829369 Free PMC article.

3

Anti-apoptotic Mcl-1 is essential for the development and sustained growth of acute myeloid leukemia.

Glaser SP, Lee EF, Trounson E, Bouillet P, Wei A, Fairlie WD, Izon DJ, Zuber J, Rappaport AR, Herold MJ, Alexander WS, Lowe SW, Robb L, Strasser A. Glaser SP, et al. Among authors: herold mj. Genes Dev. 2012 Jan 15;26(2):120-5. doi: 10.1101/gad.182980.111. Genes Dev. 2012. PMID: 22279045 Free PMC article.

4

The BH3-only proteins Bim and Puma cooperate to impose deletional tolerance of organ-specific antigens.

Gray DH, Kupresanin F, Berzins SP, Herold MJ, O'Reilly LA, Bouillet P, Strasser A. Gray DH, et al. Among authors: herold mj. Immunity. 2012 Sep 21;37(3):451-62. doi: 10.1016/j.immuni.2012.05.030. Epub 2012 Sep 6. Immunity. 2012. PMID: 22960223 Free PMC article.

5

Mutually exclusive regulation of T cell survival by IL-7R and antigen receptor-induced signals.

Koenen P, Heinzel S, Carrington EM, Happo L, Alexander WS, Zhang JG, Herold MJ, Scott CL, Lew AM, Strasser A, Hodgkin PD. Koenen P, et al. Among authors: herold mj. Nat Commun. 2013;4:1735. doi: 10.1038/ncomms2719. Nat Commun. 2013. PMID: 23591902 Free PMC article.

6

Foxo-mediated Bim transcription is dispensable for the apoptosis of hematopoietic cells that is mediated by this BH3-only protein.

Herold MJ, Rohrbeck L, Lang MJ, Grumont R, Gerondakis S, Tai L, Bouillet P, Kaufmann T, Strasser A. Herold MJ, et al. EMBO Rep. 2013 Nov;14(11):992-8. doi: 10.1038/embor.2013.152. Epub 2013 Sep 24. EMBO Rep. 2013. PMID: 24060902 Free PMC article.

7

Targeting of MCL-1 kills MYC-driven mouse and human lymphomas even when they bear mutations in p53.

Kelly GL, Grabow S, Glaser SP, Fitzsimmons L, Aubrey BJ, Okamoto T, Valente LJ, Robati M, Tai L, Fairlie WD, Lee EF, Lindstrom MS, Wiman KG, Huang DC, Bouillet P, Rowe M, Rickinson AB, Herold MJ, Strasser A. Kelly GL, et al. Among authors: herold mj. Genes Dev. 2014 Jan 1;28(1):58-70. doi: 10.1101/gad.232009.113. Genes Dev. 2014. PMID: 24395247 Free PMC article.

8

It's not over until the FAT lady sings.

Herold MJ, Strasser A. Herold MJ, et al. EMBO J. 2014 Feb 3;33(3):173-5. doi: 10.1002/embj.201387542. Epub 2014 Jan 17. EMBO J. 2014. PMID: 24442638 Free PMC article.

9

Pro-apoptotic BIM is an essential initiator of physiological endothelial cell death independent of regulation by FOXO3.

Koenig MN, Naik E, Rohrbeck L, Herold MJ, Trounson E, Bouillet P, Thomas T, Voss AK, Strasser A, Coultas L. Koenig MN, et al. Among authors: herold mj. Cell Death Differ. 2014 Nov;21(11):1687-95. doi: 10.1038/cdd.2014.90. Epub 2014 Jun 27. Cell Death Differ. 2014. PMID: 24971484 Free PMC article.

10

Evidence against upstream regulation of the unfolded protein response (UPR) by pro-apoptotic BIM and PUMA.

Herold MJ, O'Reilly LA, Lin A, Srivastava R, Doerflinger M, Bouillet P, Strasser A, Puthalakath H. Herold MJ, et al. Cell Death Dis. 2014 Jul 31;5(7):e1354. doi: 10.1038/cddis.2014.290. Cell Death Dis. 2014. PMID: 25077540 Free PMC article. No abstract available.

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