Vandenberg CJ - Search Results

1

DNA repair processes are critical mediators of p53-dependent tumor suppression.

Janic A, Valente LJ, Wakefield MJ, Di Stefano L, Milla L, Wilcox S, Yang H, Tai L, Vandenberg CJ, Kueh AJ, Mizutani S, Brennan MS, Schenk RL, Lindqvist LM, Papenfuss AT, O'Connor L, Strasser A, Herold MJ. Janic A, et al. Among authors: vandenberg cj. Nat Med. 2018 Jul;24(7):947-953. doi: 10.1038/s41591-018-0043-5. Epub 2018 Jun 11. Nat Med. 2018. PMID: 29892060

2

Myeloid progenitor cells lacking p53 exhibit delayed up-regulation of Puma and prolonged survival after cytokine deprivation.

Jabbour AM, Daunt CP, Green BD, Vogel S, Gordon L, Lee RS, Silke N, Pearson RB, Vandenberg CJ, Kelly PN, Nutt SL, Strasser A, Borner C, Ekert PG. Jabbour AM, et al. Among authors: vandenberg cj. Blood. 2010 Jan 14;115(2):344-52. doi: 10.1182/blood-2009-07-230730. Epub 2009 Nov 17. Blood. 2010. PMID: 19965665 Free PMC article.

3

Apoptosis-promoted tumorigenesis: gamma-irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death.

Michalak EM, Vandenberg CJ, Delbridge AR, Wu L, Scott CL, Adams JM, Strasser A. Michalak EM, et al. Among authors: vandenberg cj. Genes Dev. 2010 Aug 1;24(15):1608-13. doi: 10.1101/gad.1940110. Genes Dev. 2010. PMID: 20679396 Free PMC article.

4

Maximal killing of lymphoma cells by DNA damage-inducing therapy requires not only the p53 targets Puma and Noxa, but also Bim.

Happo L, Cragg MS, Phipson B, Haga JM, Jansen ES, Herold MJ, Dewson G, Michalak EM, Vandenberg CJ, Smyth GK, Strasser A, Cory S, Scott CL. Happo L, et al. Among authors: vandenberg cj. Blood. 2010 Dec 9;116(24):5256-67. doi: 10.1182/blood-2010-04-280818. Epub 2010 Sep 9. Blood. 2010. PMID: 20829369 Free PMC article.

5

DNA damage-induced primordial follicle oocyte apoptosis and loss of fertility require TAp63-mediated induction of Puma and Noxa.

Kerr JB, Hutt KJ, Michalak EM, Cook M, Vandenberg CJ, Liew SH, Bouillet P, Mills A, Scott CL, Findlay JK, Strasser A. Kerr JB, et al. Among authors: vandenberg cj. Mol Cell. 2012 Nov 9;48(3):343-52. doi: 10.1016/j.molcel.2012.08.017. Epub 2012 Sep 20. Mol Cell. 2012. PMID: 23000175 Free PMC article.

6

Plasmacytomagenesis in Eμ-v-abl transgenic mice is accelerated when apoptosis is restrained.

Vandenberg CJ, Waring P, Strasser A, Cory S. Vandenberg CJ, et al. Blood. 2014 Aug 14;124(7):1099-109. doi: 10.1182/blood-2014-04-570770. Epub 2014 Jul 1. Blood. 2014. PMID: 24986687 Free PMC article.

7

Innate immunodeficiency following genetic ablation of Mcl1 in natural killer cells.

Sathe P, Delconte RB, Souza-Fonseca-Guimaraes F, Seillet C, Chopin M, Vandenberg CJ, Rankin LC, Mielke LA, Vikstrom I, Kolesnik TB, Nicholson SE, Vivier E, Smyth MJ, Nutt SL, Glaser SP, Strasser A, Belz GT, Carotta S, Huntington ND. Sathe P, et al. Among authors: vandenberg cj. Nat Commun. 2014 Aug 14;5:4539. doi: 10.1038/ncomms5539. Nat Commun. 2014. PMID: 25119382 Free article.

8

Combined loss of PUMA and p21 accelerates c-MYC-driven lymphoma development considerably less than loss of one allele of p53.

Valente LJ, Grabow S, Vandenberg CJ, Strasser A, Janic A. Valente LJ, et al. Among authors: vandenberg cj. Oncogene. 2016 Jul 21;35(29):3866-71. doi: 10.1038/onc.2015.457. Epub 2015 Dec 7. Oncogene. 2016. PMID: 26640149

9

Loss of a Single Mcl-1 Allele Inhibits MYC-Driven Lymphomagenesis by Sensitizing Pro-B Cells to Apoptosis.

Grabow S, Delbridge AR, Aubrey BJ, Vandenberg CJ, Strasser A. Grabow S, et al. Among authors: vandenberg cj. Cell Rep. 2016 Mar 15;14(10):2337-47. doi: 10.1016/j.celrep.2016.02.039. Epub 2016 Mar 3. Cell Rep. 2016. PMID: 26947081 Free article.

10

RAG-induced DNA lesions activate proapoptotic BIM to suppress lymphomagenesis in p53-deficient mice.

Delbridge AR, Pang SH, Vandenberg CJ, Grabow S, Aubrey BJ, Tai L, Herold MJ, Strasser A. Delbridge AR, et al. Among authors: vandenberg cj. J Exp Med. 2016 Sep 19;213(10):2039-48. doi: 10.1084/jem.20150477. Epub 2016 Sep 12. J Exp Med. 2016. PMID: 27621418 Free PMC article.

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