Sherer EC - Search Results

1

Post-Synthetic Modification of Oligonucleotides via Orthogonal Amidation and Copper Catalyzed Cycloaddition Reactions.

Zewge D, Butora G, Sherer EC, Tellers DM, Sidler DR, Gouker J, Copeland G, Jadhav V, Li Z, Armstrong J, Davies IW. Zewge D, et al. Among authors: sherer ec. Bioconjug Chem. 2018 Jun 20;29(6):1859-1865. doi: 10.1021/acs.bioconjchem.8b00298. Epub 2018 Jun 12. Bioconjug Chem. 2018. PMID: 29893553

2

Systematic chemical modifications of single stranded siRNAs significantly improved CTNNB1 mRNA silencing.

Chang W, Pei Y, Guidry EN, Zewge D, Parish CA, Sherer EC, DiMuzio J, Zhang H, South VJ, Strapps WR, Sepp-Lorenzino L, Colletti SL, Stanton MG. Chang W, et al. Among authors: sherer ec. Bioorg Med Chem Lett. 2016 Sep 15;26(18):4513-4517. doi: 10.1016/j.bmcl.2016.07.064. Epub 2016 Jul 28. Bioorg Med Chem Lett. 2016. PMID: 27503684

3

A multifunctional catalyst that stereoselectively assembles prodrugs.

DiRocco DA, Ji Y, Sherer EC, Klapars A, Reibarkh M, Dropinski J, Mathew R, Maligres P, Hyde AM, Limanto J, Brunskill A, Ruck RT, Campeau LC, Davies IW. DiRocco DA, et al. Among authors: sherer ec. Science. 2017 Apr 28;356(6336):426-430. doi: 10.1126/science.aam7936. Science. 2017. PMID: 28450641

4

A rational pre-catalyst design for bis-phosphine mono-oxide palladium catalyzed reactions.

Ji Y, Li H, Hyde AM, Chen Q, Belyk KM, Lexa KW, Yin J, Sherer EC, Williamson RT, Brunskill A, Ren S, Campeau LC, Davies IW, Ruck RT. Ji Y, et al. Among authors: sherer ec. Chem Sci. 2017 Apr 1;8(4):2841-2851. doi: 10.1039/c6sc05472b. Epub 2017 Jan 19. Chem Sci. 2017. PMID: 28553522 Free PMC article.

5

Beyond optical rotation: what's left is not always right in total synthesis.

Joyce LA, Nawrat CC, Sherer EC, Biba M, Brunskill A, Martin GE, Cohen RD, Davies IW. Joyce LA, et al. Among authors: sherer ec. Chem Sci. 2017 Oct 30;9(2):415-424. doi: 10.1039/c7sc04249c. eCollection 2018 Jan 14. Chem Sci. 2017. PMID: 29629112 Free PMC article.

6

Sustainable Practices in Medicinal Chemistry Part 2: Green by Design.

Aliagas I, Berger R, Goldberg K, Nishimura RT, Reilly J, Richardson P, Richter D, Sherer EC, Sparling BA, Bryan MC. Aliagas I, et al. Among authors: sherer ec. J Med Chem. 2017 Jul 27;60(14):5955-5968. doi: 10.1021/acs.jmedchem.6b01837. Epub 2017 Apr 12. J Med Chem. 2017. PMID: 28375009 Review.

7

Model for the Enantioselectivity of Asymmetric Intramolecular Alkylations by Bis-Quaternized Cinchona Alkaloid-Derived Catalysts.

He CQ, Simon A, Lam YH, Brunskill APJ, Yasuda N, Tan J, Hyde AM, Sherer EC, Houk KN. He CQ, et al. Among authors: sherer ec. J Org Chem. 2017 Aug 18;82(16):8645-8650. doi: 10.1021/acs.joc.7b01577. Epub 2017 Jul 31. J Org Chem. 2017. PMID: 28731701

8

Highly Diastereoselective Synthesis of a HCV NS5B Nucleoside Polymerase Inhibitor.

Zhong YL, Cleator E, Liu Z, Yin J, Morris WJ, Alam M, Bishop B, Dumas AM, Edwards J, Goodyear A, Mullens P, Song ZJ, Shevlin M, Thaisrivongs DA, Li H, Sherer EC, Cohen RD, Yin J, Tan L, Yasuda N, Limanto J, Davies A, Campos KR. Zhong YL, et al. Among authors: sherer ec. J Org Chem. 2019 Apr 19;84(8):4780-4795. doi: 10.1021/acs.joc.8b02500. Epub 2018 Dec 10. J Org Chem. 2019. PMID: 30475616

9

The merger of decatungstate and copper catalysis to enable aliphatic C(sp³)-H trifluoromethylation.

Sarver PJ, Bacauanu V, Schultz DM, DiRocco DA, Lam YH, Sherer EC, MacMillan DWC. Sarver PJ, et al. Among authors: sherer ec. Nat Chem. 2020 May;12(5):459-467. doi: 10.1038/s41557-020-0436-1. Epub 2020 Mar 16. Nat Chem. 2020. PMID: 32203440

10

Analysis of Benzenoid Substitution Patterns in Small Molecule Active Pharmaceutical Ingredients.

Nilova A, Campeau LC, Sherer EC, Stuart DR. Nilova A, et al. Among authors: sherer ec. J Med Chem. 2020 Nov 25;63(22):13389-13396. doi: 10.1021/acs.jmedchem.0c00915. Epub 2020 Aug 31. J Med Chem. 2020. PMID: 32786676

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