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Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC).
Chu Y, Zhao Z, Sant DW, Zhu G, Greenblatt SM, Liu L, Wang J, Cao Z, Tho JC, Chen S, Liu X, Zhang P, Maciejewski JP, Nimer S, Wang G, Yuan W, Yang FC, Xu M. Chu Y, et al. Among authors: chen s. Genomics Proteomics Bioinformatics. 2018 Jun;16(3):172-186. doi: 10.1016/j.gpb.2018.04.005. Epub 2018 Jun 13. Genomics Proteomics Bioinformatics. 2018. PMID: 29908294 Free PMC article.
Ex vivo culture of Fancc-/- stem/progenitor cells predisposes cells to undergo apoptosis, and surviving stem/progenitor cells display cytogenetic abnormalities and an increased risk of malignancy.
Li X, Le Beau MM, Ciccone S, Yang FC, Freie B, Chen S, Yuan J, Hong P, Orazi A, Haneline LS, Clapp DW. Li X, et al. Among authors: chen s. Blood. 2005 May 1;105(9):3465-71. doi: 10.1182/blood-2004-06-2483. Epub 2005 Jan 11. Blood. 2005. PMID: 15644418 Free PMC article.
The p85alpha subunit of class IA phosphatidylinositol 3-kinase regulates the expression of multiple genes involved in osteoclast maturation and migration.
Munugalavadla V, Vemula S, Sims EC, Krishnan S, Chen S, Yan J, Li H, Niziolek PJ, Takemoto C, Robling AG, Yang FC, Kapur R. Munugalavadla V, et al. Among authors: chen s. Mol Cell Biol. 2008 Dec;28(23):7182-98. doi: 10.1128/MCB.00920-08. Epub 2008 Sep 22. Mol Cell Biol. 2008. PMID: 18809581 Free PMC article.
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