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Integrating biomarkers across omic platforms: an approach to improve stratification of patients with indolent and aggressive prostate cancer.
Murphy K, Murphy BT, Boyce S, Flynn L, Gilgunn S, O'Rourke CJ, Rooney C, Stöckmann H, Walsh AL, Finn S, O'Kennedy RJ, O'Leary J, Pennington SR, Perry AS, Rudd PM, Saldova R, Sheils O, Shields DC, Watson RW. Murphy K, et al. Mol Oncol. 2018 Sep;12(9):1513-1525. doi: 10.1002/1878-0261.12348. Epub 2018 Aug 7. Mol Oncol. 2018. PMID: 29927052 Free PMC article.
Mining methylome databases.
O'Rourke CJ, Murphy TM, Hollywood D, Perry AS. O'Rourke CJ, et al. Trends Genet. 2013 Feb;29(2):63-5. doi: 10.1016/j.tig.2012.10.015. Epub 2012 Nov 23. Trends Genet. 2013. PMID: 23182652 No abstract available.
Manipulating the epigenome for the treatment of urological malignancies.
O'Rourke CJ, Knabben V, Bolton E, Moran D, Lynch T, Hollywood D, Perry AS. O'Rourke CJ, et al. Pharmacol Ther. 2013 May;138(2):185-96. doi: 10.1016/j.pharmthera.2013.01.007. Epub 2013 Jan 24. Pharmacol Ther. 2013. PMID: 23353098 Free PMC article. Review.
Epigenome Remodeling in Cholangiocarcinoma.
O'Rourke CJ, Lafuente-Barquero J, Andersen JB. O'Rourke CJ, et al. Trends Cancer. 2019 Jun;5(6):335-350. doi: 10.1016/j.trecan.2019.05.002. Epub 2019 Jun 4. Trends Cancer. 2019. PMID: 31208696 Review.
Epigenetic modifications precede molecular alterations and drive human hepatocarcinogenesis.
Czauderna C, Poplawski A, O'Rourke CJ, Castven D, Pérez-Aguilar B, Becker D, Heilmann-Heimbach S, Odenthal M, Amer W, Schmiel M, Drebber U, Binder H, Ridder DA, Schindeldecker M, Straub BK, Galle PR, Andersen JB, Thorgeirsson SS, Park YN, Marquardt JU. Czauderna C, et al. JCI Insight. 2021 Sep 8;6(17):e146196. doi: 10.1172/jci.insight.146196. JCI Insight. 2021. PMID: 34375307 Free PMC article.
Mutational signatures and processes in hepatobiliary cancers.
Zhuravleva E, O'Rourke CJ, Andersen JB. Zhuravleva E, et al. Among authors: o rourke cj. Nat Rev Gastroenterol Hepatol. 2022 Jun;19(6):367-382. doi: 10.1038/s41575-022-00587-w. Epub 2022 Mar 10. Nat Rev Gastroenterol Hepatol. 2022. PMID: 35273358 Review.
38 results