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IBD risk loci are enriched in multigenic regulatory modules encompassing putative causative genes.
Momozawa Y, Dmitrieva J, Théâtre E, Deffontaine V, Rahmouni S, Charloteaux B, Crins F, Docampo E, Elansary M, Gori AS, Lecut C, Mariman R, Mni M, Oury C, Altukhov I, Alexeev D, Aulchenko Y, Amininejad L, Bouma G, Hoentjen F, Löwenberg M, Oldenburg B, Pierik MJ, Vander Meulen-de Jong AE, Janneke van der Woude C, Visschedijk MC; International IBD Genetics Consortium; Lathrop M, Hugot JP, Weersma RK, De Vos M, Franchimont D, Vermeire S, Kubo M, Louis E, Georges M. Momozawa Y, et al. Among authors: rahmouni s. Nat Commun. 2018 Jun 21;9(1):2427. doi: 10.1038/s41467-018-04365-8. Nat Commun. 2018. PMID: 29930244 Free PMC article.
Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility.
Sazonovs A, Stevens CR, Venkataraman GR, Yuan K, Avila B, Abreu MT, Ahmad T, Allez M, Ananthakrishnan AN, Atzmon G, Baras A, Barrett JC, Barzilai N, Beaugerie L, Beecham A, Bernstein CN, Bitton A, Bokemeyer B, Chan A, Chung D, Cleynen I, Cosnes J, Cutler DJ, Daly A, Damas OM, Datta LW, Dawany N, Devoto M, Dodge S, Ellinghaus E, Fachal L, Farkkila M, Faubion W, Ferreira M, Franchimont D, Gabriel SB, Ge T, Georges M, Gettler K, Giri M, Glaser B, Goerg S, Goyette P, Graham D, Hämäläinen E, Haritunians T, Heap GA, Hiltunen M, Hoeppner M, Horowitz JE, Irving P, Iyer V, Jalas C, Kelsen J, Khalili H, Kirschner BS, Kontula K, Koskela JT, Kugathasan S, Kupcinskas J, Lamb CA, Laudes M, Lévesque C, Levine AP, Lewis JD, Liefferinckx C, Loescher BS, Louis E, Mansfield J, May S, McCauley JL, Mengesha E, Mni M, Moayyedi P, Moran CJ, Newberry RD, O'Charoen S, Okou DT, Oldenburg B, Ostrer H, Palotie A, Paquette J, Pekow J, Peter I, Pierik MJ, Ponsioen CY, Pontikos N, Prescott N, Pulver AE, Rahmouni S, Rice DL, Saavalainen P, Sands B, Sartor RB, Schiff ER, Schreiber S, Schumm LP, Segal AW, Seksik P, Shawky R, Sheikh SZ, Silverberg MS, Simmons A, Skeiceviciene J, Sokol H, Solomonson M, Somine… See abstract for full author list ➔ Sazonovs A, et al. Among authors: rahmouni s. Nat Genet. 2022 Sep;54(9):1275-1283. doi: 10.1038/s41588-022-01156-2. Epub 2022 Aug 29. Nat Genet. 2022. PMID: 36038634 Free PMC article.
Identification of tissue-specific and common methylation quantitative trait loci in healthy individuals using MAGAR.
Scherer M, Gasparoni G, Rahmouni S, Shashkova T, Arnoux M, Louis E, Nostaeva A, Avalos D, Dermitzakis ET, Aulchenko YS, Lengauer T, Lyons PA, Georges M, Walter J. Scherer M, et al. Among authors: rahmouni s. Epigenetics Chromatin. 2021 Sep 16;14(1):44. doi: 10.1186/s13072-021-00415-6. Epigenetics Chromatin. 2021. PMID: 34530905 Free PMC article.
[Antiplatelet drugs: what's new?].
Oury C, Rahmouni S, Lancellotti P. Oury C, et al. Among authors: rahmouni s. Med Sci (Paris). 2015 Aug-Sep;31(8-9):720-2. doi: 10.1051/medsci/20153108006. Epub 2015 Sep 4. Med Sci (Paris). 2015. PMID: 26340827 Free article. French. No abstract available.
Dual-specificity phosphatase 3 deficiency or inhibition limits platelet activation and arterial thrombosis.
Musumeci L, Kuijpers MJ, Gilio K, Hego A, Théâtre E, Maurissen L, Vandereyken M, Diogo CV, Lecut C, Guilmain W, Bobkova EV, Eble JA, Dahl R, Drion P, Rascon J, Mostofi Y, Yuan H, Sergienko E, Chung TD, Thiry M, Senis Y, Moutschen M, Mustelin T, Lancellotti P, Heemskerk JW, Tautz L, Oury C, Rahmouni S. Musumeci L, et al. Among authors: rahmouni s. Circulation. 2015 Feb 17;131(7):656-68. doi: 10.1161/CIRCULATIONAHA.114.010186. Epub 2014 Dec 17. Circulation. 2015. PMID: 25520375 Free PMC article.
Dual-specificity phosphatase 3 deletion promotes obesity, non-alcoholic steatohepatitis and hepatocellular carcinoma.
Jacques S, Arjomand A, Perée H, Collins P, Mayer A, Lavergne A, Wéry M, Mni M, Hego A, Thuillier V, Becker G, Bahri MA, Plenevaux A, Di Valentin E, Oury C, Moutschen M, Delvenne P, Paquot N, Rahmouni S. Jacques S, et al. Among authors: rahmouni s. Sci Rep. 2021 Mar 12;11(1):5817. doi: 10.1038/s41598-021-85089-6. Sci Rep. 2021. PMID: 33712680 Free PMC article.
Mapping the human genetic architecture of COVID-19.
COVID-19 Host Genetics Initiative. COVID-19 Host Genetics Initiative. Nature. 2021 Dec;600(7889):472-477. doi: 10.1038/s41586-021-03767-x. Epub 2021 Jul 8. Nature. 2021. PMID: 34237774 Free PMC article.
Targeting of C-type lectin-like receptor 2 or P2Y12 for the prevention of platelet activation by immunotherapeutic CpG oligodeoxynucleotides.
Delierneux C, Donis N, Servais L, Wéra O, Lecut C, Vandereyken M, Musumeci L, Rahmouni S, Schneider J, Eble JA, Lancellotti P, Oury C. Delierneux C, et al. Among authors: rahmouni s. J Thromb Haemost. 2017 May;15(5):983-997. doi: 10.1111/jth.13669. Epub 2017 Apr 13. J Thromb Haemost. 2017. PMID: 28296036 Free article.
105 results