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Nanoscale dysregulation of collagen structure-function disrupts mechano-homeostasis and mediates pulmonary fibrosis.
Jones MG, Andriotis OG, Roberts JJ, Lunn K, Tear VJ, Cao L, Ask K, Smart DE, Bonfanti A, Johnson P, Alzetani A, Conforti F, Doherty R, Lai CY, Johnson B, Bourdakos KN, Fletcher SV, Marshall BG, Jogai S, Brereton CJ, Chee SJ, Ottensmeier CH, Sime P, Gauldie J, Kolb M, Mahajan S, Fabre A, Bhaskar A, Jarolimek W, Richeldi L, O'Reilly KM, Monk PD, Thurner PJ, Davies DE. Jones MG, et al. Among authors: fletcher sv. Elife. 2018 Jul 3;7:e36354. doi: 10.7554/eLife.36354. Elife. 2018. PMID: 29966587 Free PMC article.
The safety of new drug treatments for idiopathic pulmonary fibrosis.
Fletcher S, Jones MG, Spinks K, Sgalla G, Marshall BG, Limbrey R, Richeldi L. Fletcher S, et al. Expert Opin Drug Saf. 2016 Nov;15(11):1483-1489. doi: 10.1080/14740338.2016.1218470. Epub 2016 Aug 17. Expert Opin Drug Saf. 2016. PMID: 27532218 Review.
Paracrine signalling during ZEB1-mediated epithelial-mesenchymal transition augments local myofibroblast differentiation in lung fibrosis.
Yao L, Conforti F, Hill C, Bell J, Drawater L, Li J, Liu D, Xiong H, Alzetani A, Chee SJ, Marshall BG, Fletcher SV, Hancock D, Coldwell M, Yuan X, Ottensmeier CH, Downward J, Collins JE, Ewing RM, Richeldi L, Skipp P, Jones MG, Davies DE, Wang Y. Yao L, et al. Among authors: fletcher sv. Cell Death Differ. 2019 May;26(5):943-957. doi: 10.1038/s41418-018-0175-7. Epub 2018 Jul 26. Cell Death Differ. 2019. PMID: 30050057 Free PMC article.
Safety and tolerability of nintedanib for the treatment of idiopathic pulmonary fibrosis in routine UK clinical practice.
Fletcher SV, Jones MG, Renzoni EA, Parfrey H, Hoyles RK, Spinks K, Kokosi M, Kwok A, Warburton C, Titmuss V, Thillai M, Simler N, Maher TM, Brereton CJ, Chua F, Wells AU, Richeldi L, Spencer LG. Fletcher SV, et al. ERJ Open Res. 2018 Oct 19;4(4):00049-2018. doi: 10.1183/23120541.00049-2018. eCollection 2018 Oct. ERJ Open Res. 2018. PMID: 30364342 Free PMC article.
Autophagy inhibition-mediated epithelial-mesenchymal transition augments local myofibroblast differentiation in pulmonary fibrosis.
Hill C, Li J, Liu D, Conforti F, Brereton CJ, Yao L, Zhou Y, Alzetani A, Chee SJ, Marshall BG, Fletcher SV, Hancock D, Ottensmeier CH, Steele AJ, Downward J, Richeldi L, Lu X, Davies DE, Jones MG, Wang Y. Hill C, et al. Among authors: fletcher sv. Cell Death Dis. 2019 Aug 7;10(8):591. doi: 10.1038/s41419-019-1820-x. Cell Death Dis. 2019. PMID: 31391462 Free PMC article.
26 results