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Targeting Cdc42 with the anticancer compound MBQ-167 inhibits cell polarity and growth in the budding yeast S. cerevisiae.
Small GTPases. 2020 Nov;11(6):430-440. doi: 10.1080/21541248.2018.1495008. Epub 2018 Jul 29.
Small GTPases. 2020.
PMID: 29969362
Free PMC article.
Characterization of a Dual Rac/Cdc42 Inhibitor MBQ-167 in Metastatic Cancer.
Humphries-Bickley T, Castillo-Pichardo L, Hernandez-O'Farrill E, Borrero-Garcia LD, Forestier-Roman I, Gerena Y, Blanco M, Rivera-Robles MJ, Rodriguez-Medina JR, Cubano LA, Vlaar CP, Dharmawardhane S.
Humphries-Bickley T, et al. Among authors: rivera robles mj.
Mol Cancer Ther. 2017 May;16(5):805-818. doi: 10.1158/1535-7163.MCT-16-0442.
Mol Cancer Ther. 2017.
PMID: 28450422
Free PMC article.
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Rac and Cdc42 inhibitors reduce macrophage function in breast cancer preclinical models.
Torres-Sanchez A, Rivera-Robles M, Castillo-Pichardo L, Martínez-Ferrer M, Dorta-Estremera SM, Dharmawardhane S.
Torres-Sanchez A, et al.
Front Oncol. 2023 Jun 16;13:1152458. doi: 10.3389/fonc.2023.1152458. eCollection 2023.
Front Oncol. 2023.
PMID: 37397366
Free PMC article.
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