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Nonclinical and human pharmacology of the potent and selective topical retinoic acid receptor-γ agonist trifarotene.
Aubert J, Piwnica D, Bertino B, Blanchet-Réthoré S, Carlavan I, Déret S, Dreno B, Gamboa B, Jomard A, Luzy AP, Mauvais P, Mounier C, Pascau J, Pelisson I, Portal T, Rivier M, Rossio P, Thoreau E, Vial E, Voegel JJ. Aubert J, et al. Among authors: carlavan i. Br J Dermatol. 2018 Aug;179(2):442-456. doi: 10.1111/bjd.16719. Epub 2018 Jul 4. Br J Dermatol. 2018. PMID: 29974453 Clinical Trial.
Discovery and Characterization of CD12681, a Potent RORγ Inverse Agonist, Preclinical Candidate for the Topical Treatment of Psoriasis.
Ouvry G, Atrux-Tallau N, Bihl F, Bondu A, Bouix-Peter C, Carlavan I, Christin O, Cuadrado MJ, Defoin-Platel C, Deret S, Duvert D, Feret C, Forissier M, Fournier JF, Froude D, Hacini-Rachinel F, Harris CS, Hervouet C, Huguet H, Lafitte G, Luzy AP, Musicki B, Orfila D, Ozello B, Pascau C, Pascau J, Parnet V, Peluchon G, Pierre R, Piwnica D, Raffin C, Rossio P, Spiesse D, Taquet N, Thoreau E, Vatinel R, Vial E, Hennequin LF. Ouvry G, et al. Among authors: carlavan i. ChemMedChem. 2018 Feb 20;13(4):321-337. doi: 10.1002/cmdc.201700758. Epub 2018 Feb 6. ChemMedChem. 2018. PMID: 29327456
Neurovascular and neuroimmune aspects in the pathophysiology of rosacea.
Schwab VD, Sulk M, Seeliger S, Nowak P, Aubert J, Mess C, Rivier M, Carlavan I, Rossio P, Metze D, Buddenkotte J, Cevikbas F, Voegel JJ, Steinhoff M. Schwab VD, et al. Among authors: carlavan i. J Investig Dermatol Symp Proc. 2011 Dec;15(1):53-62. doi: 10.1038/jidsymp.2011.6. J Investig Dermatol Symp Proc. 2011. PMID: 22076328 Free PMC article.
Clinical, cellular, and molecular aspects in the pathophysiology of rosacea.
Steinhoff M, Buddenkotte J, Aubert J, Sulk M, Novak P, Schwab VD, Mess C, Cevikbas F, Rivier M, Carlavan I, Déret S, Rosignoli C, Metze D, Luger TA, Voegel JJ. Steinhoff M, et al. Among authors: carlavan i. J Investig Dermatol Symp Proc. 2011 Dec;15(1):2-11. doi: 10.1038/jidsymp.2011.7. J Investig Dermatol Symp Proc. 2011. PMID: 22076321 Free PMC article. Review.
IL-17/Th17 pathway is activated in acne lesions.
Kelhälä HL, Palatsi R, Fyhrquist N, Lehtimäki S, Väyrynen JP, Kallioinen M, Kubin ME, Greco D, Tasanen K, Alenius H, Bertino B, Carlavan I, Mehul B, Déret S, Reiniche P, Martel P, Marty C, Blume-Peytavi U, Voegel JJ, Lauerma A. Kelhälä HL, et al. Among authors: carlavan i. PLoS One. 2014 Aug 25;9(8):e105238. doi: 10.1371/journal.pone.0105238. eCollection 2014. PLoS One. 2014. PMID: 25153527 Free PMC article.
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