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Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.
Sharma A, Halu A, Decano JL, Padi M, Liu YY, Prasad RB, Fadista J, Santolini M, Menche J, Weiss ST, Vidal M, Silverman EK, Aikawa M, Barabási AL, Groop L, Loscalzo J. Sharma A, et al. Among authors: decano jl. NPJ Syst Biol Appl. 2018 Jul 3;4:25. doi: 10.1038/s41540-018-0057-0. eCollection 2018. NPJ Syst Biol Appl. 2018. PMID: 29977601 Free PMC article.
Macrophage Notch Ligand Delta-Like 4 Promotes Vein Graft Lesion Development: Implications for the Treatment of Vein Graft Failure.
Koga JI, Nakano T, Dahlman JE, Figueiredo JL, Zhang H, Decano J, Khan OF, Niida T, Iwata H, Aster JC, Yagita H, Anderson DG, Ozaki CK, Aikawa M. Koga JI, et al. Among authors: decano j. Arterioscler Thromb Vasc Biol. 2015 Nov;35(11):2343-2353. doi: 10.1161/ATVBAHA.115.305516. Epub 2015 Sep 24. Arterioscler Thromb Vasc Biol. 2015. PMID: 26404485 Free PMC article.
Uremic Toxin Indoxyl Sulfate Promotes Proinflammatory Macrophage Activation Via the Interplay of OATP2B1 and Dll4-Notch Signaling.
Nakano T, Katsuki S, Chen M, Decano JL, Halu A, Lee LH, Pestana DVS, Kum AST, Kuromoto RK, Golden WS, Boff MS, Guimaraes GC, Higashi H, Kauffman KJ, Maejima T, Suzuki T, Iwata H, Barabási AL, Aster JC, Anderson DG, Sharma A, Singh SA, Aikawa E, Aikawa M. Nakano T, et al. Among authors: decano jl. Circulation. 2019 Jan 2;139(1):78-96. doi: 10.1161/CIRCULATIONAHA.118.034588. Circulation. 2019. PMID: 30586693 Free PMC article.
Systems Approach to Discovery of Therapeutic Targets for Vein Graft Disease: PPARα Pivotally Regulates Metabolism, Activation, and Heterogeneity of Macrophages and Lesion Development.
Decano JL, Singh SA, Gasparotto Bueno C, Ho Lee L, Halu A, Chelvanambi S, Matamalas JT, Zhang H, Mlynarchik AK, Qiao J, Sharma A, Mukai S, Wang J, Anderson DG, Ozaki CK, Libby P, Aikawa E, Aikawa M. Decano JL, et al. Circulation. 2021 Jun 22;143(25):2454-2470. doi: 10.1161/CIRCULATIONAHA.119.043724. Epub 2021 Apr 6. Circulation. 2021. PMID: 33821665 Free PMC article.
A disease-driver population within interstitial cells of human calcific aortic valves identified via single-cell and proteomic profiling.
Decano JL, Iwamoto Y, Goto S, Lee JY, Matamalas JT, Halu A, Blaser M, Lee LH, Pieper B, Chelvanambi S, Silva-Nicolau J, Bartoli-Leonard F, Higashi H, Shibata H, Vyas P, Wang J, Gostjeva E, Body SC, Singh SA, Aikawa M, Aikawa E. Decano JL, et al. Cell Rep. 2022 Apr 12;39(2):110685. doi: 10.1016/j.celrep.2022.110685. Cell Rep. 2022. PMID: 35417712 Free article.
Proprotein Convertase Subtilisin/Kexin 9 (PCSK9) Promotes Macrophage Activation via LDL Receptor-Independent Mechanisms.
Katsuki S, K Jha P, Lupieri A, Nakano T, Passos LSA, Rogers MA, Becker-Greene D, Le TD, Decano JL, Ho Lee L, Guimaraes GC, Abdelhamid I, Halu A, Muscoloni A, V Cannistraci C, Higashi H, Zhang H, Vromman A, Libby P, Keith Ozaki C, Sharma A, Singh SA, Aikawa E, Aikawa M. Katsuki S, et al. Among authors: decano jl. Circ Res. 2022 Nov 11;131(11):873-889. doi: 10.1161/CIRCRESAHA.121.320056. Epub 2022 Oct 20. Circ Res. 2022. PMID: 36263780 Free PMC article.
25 results