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Controllability in an islet specific regulatory network identifies the transcriptional factor NFATC4, which regulates Type 2 Diabetes associated genes.
Sharma A, Halu A, Decano JL, Padi M, Liu YY, Prasad RB, Fadista J, Santolini M, Menche J, Weiss ST, Vidal M, Silverman EK, Aikawa M, Barabási AL, Groop L, Loscalzo J. Sharma A, et al. Among authors: vidal m. NPJ Syst Biol Appl. 2018 Jul 3;4:25. doi: 10.1038/s41540-018-0057-0. eCollection 2018. NPJ Syst Biol Appl. 2018. PMID: 29977601 Free PMC article.
Genome-scale analysis of in vivo spatiotemporal promoter activity in Caenorhabditis elegans.
Dupuy D, Bertin N, Hidalgo CA, Venkatesan K, Tu D, Lee D, Rosenberg J, Svrzikapa N, Blanc A, Carnec A, Carvunis AR, Pulak R, Shingles J, Reece-Hoyes J, Hunt-Newbury R, Viveiros R, Mohler WA, Tasan M, Roth FP, Le Peuch C, Hope IA, Johnsen R, Moerman DG, Barabási AL, Baillie D, Vidal M. Dupuy D, et al. Among authors: vidal m. Nat Biotechnol. 2007 Jun;25(6):663-8. doi: 10.1038/nbt1305. Epub 2007 May 7. Nat Biotechnol. 2007. PMID: 17486083
The human disease network.
Goh KI, Cusick ME, Valle D, Childs B, Vidal M, Barabási AL. Goh KI, et al. Among authors: vidal m. Proc Natl Acad Sci U S A. 2007 May 22;104(21):8685-90. doi: 10.1073/pnas.0701361104. Epub 2007 May 14. Proc Natl Acad Sci U S A. 2007. PMID: 17502601 Free PMC article.
Drug-target network.
Yildirim MA, Goh KI, Cusick ME, Barabási AL, Vidal M. Yildirim MA, et al. Among authors: vidal m. Nat Biotechnol. 2007 Oct;25(10):1119-26. doi: 10.1038/nbt1338. Nat Biotechnol. 2007. PMID: 17921997
High-quality binary protein interaction map of the yeast interactome network.
Yu H, Braun P, Yildirim MA, Lemmens I, Venkatesan K, Sahalie J, Hirozane-Kishikawa T, Gebreab F, Li N, Simonis N, Hao T, Rual JF, Dricot A, Vazquez A, Murray RR, Simon C, Tardivo L, Tam S, Svrzikapa N, Fan C, de Smet AS, Motyl A, Hudson ME, Park J, Xin X, Cusick ME, Moore T, Boone C, Snyder M, Roth FP, Barabási AL, Tavernier J, Hill DE, Vidal M. Yu H, et al. Among authors: vidal m. Science. 2008 Oct 3;322(5898):104-10. doi: 10.1126/science.1158684. Epub 2008 Aug 21. Science. 2008. PMID: 18719252 Free PMC article.
Interactome networks and human disease.
Vidal M, Cusick ME, Barabási AL. Vidal M, et al. Cell. 2011 Mar 18;144(6):986-98. doi: 10.1016/j.cell.2011.02.016. Cell. 2011. PMID: 21414488 Free PMC article. Review.
Viral perturbations of host networks reflect disease etiology.
Gulbahce N, Yan H, Dricot A, Padi M, Byrdsong D, Franchi R, Lee DS, Rozenblatt-Rosen O, Mar JC, Calderwood MA, Baldwin A, Zhao B, Santhanam B, Braun P, Simonis N, Huh KW, Hellner K, Grace M, Chen A, Rubio R, Marto JA, Christakis NA, Kieff E, Roth FP, Roecklein-Canfield J, Decaprio JA, Cusick ME, Quackenbush J, Hill DE, Münger K, Vidal M, Barabási AL. Gulbahce N, et al. Among authors: vidal m. PLoS Comput Biol. 2012;8(6):e1002531. doi: 10.1371/journal.pcbi.1002531. Epub 2012 Jun 28. PLoS Comput Biol. 2012. PMID: 22761553 Free PMC article.
Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.
Rozenblatt-Rosen O, Deo RC, Padi M, Adelmant G, Calderwood MA, Rolland T, Grace M, Dricot A, Askenazi M, Tavares M, Pevzner SJ, Abderazzaq F, Byrdsong D, Carvunis AR, Chen AA, Cheng J, Correll M, Duarte M, Fan C, Feltkamp MC, Ficarro SB, Franchi R, Garg BK, Gulbahce N, Hao T, Holthaus AM, James R, Korkhin A, Litovchick L, Mar JC, Pak TR, Rabello S, Rubio R, Shen Y, Singh S, Spangle JM, Tasan M, Wanamaker S, Webber JT, Roecklein-Canfield J, Johannsen E, Barabási AL, Beroukhim R, Kieff E, Cusick ME, Hill DE, Münger K, Marto JA, Quackenbush J, Roth FP, DeCaprio JA, Vidal M. Rozenblatt-Rosen O, et al. Among authors: vidal m. Nature. 2012 Jul 26;487(7408):491-5. doi: 10.1038/nature11288. Nature. 2012. PMID: 22810586 Free PMC article.
1,937 results