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Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer.
Zhao N, Cao J, Xu L, Tang Q, Dobrolecki LE, Lv X, Talukdar M, Lu Y, Wang X, Hu DZ, Shi Q, Xiang Y, Wang Y, Liu X, Bu W, Jiang Y, Li M, Gong Y, Sun Z, Ying H, Yuan B, Lin X, Feng XH, Hartig SM, Li F, Shen H, Chen Y, Han L, Zeng Q, Patterson JB, Kaipparettu BA, Putluri N, Sicheri F, Rosen JM, Lewis MT, Chen X. Zhao N, et al. Among authors: chen x, chen y. J Clin Invest. 2018 Apr 2;128(4):1283-1299. doi: 10.1172/JCI95873. Epub 2018 Feb 26. J Clin Invest. 2018. PMID: 29480818 Free PMC article.
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway.
Chen X, Iliopoulos D, Zhang Q, Tang Q, Greenblatt MB, Hatziapostolou M, Lim E, Tam WL, Ni M, Chen Y, Mai J, Shen H, Hu DZ, Adoro S, Hu B, Song M, Tan C, Landis MD, Ferrari M, Shin SJ, Brown M, Chang JC, Liu XS, Glimcher LH. Chen X, et al. Among authors: chen y. Nature. 2014 Apr 3;508(7494):103-107. doi: 10.1038/nature13119. Epub 2014 Mar 23. Nature. 2014. PMID: 24670641 Free PMC article.
IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection.
Adoro S, Cubillos-Ruiz JR, Chen X, Deruaz M, Vrbanac VD, Song M, Park S, Murooka TT, Dudek TE, Luster AD, Tager AM, Streeck H, Bowman B, Walker BD, Kwon DS, Lazarevic V, Glimcher LH. Adoro S, et al. Among authors: chen x. Nat Commun. 2015 Jun 25;6:7562. doi: 10.1038/ncomms8562. Nat Commun. 2015. PMID: 26108174 Free PMC article.
Endoplasmic Reticulum Stress in Bone Metastases.
Xu L, Zhang W, Zhang XH, Chen X. Xu L, et al. Among authors: chen x. Front Oncol. 2020 Jul 24;10:1100. doi: 10.3389/fonc.2020.01100. eCollection 2020. Front Oncol. 2020. PMID: 32850317 Free PMC article. Review.
Comprehensive characterization of circular RNAs in ~ 1000 human cancer cell lines.
Ruan H, Xiang Y, Ko J, Li S, Jing Y, Zhu X, Ye Y, Zhang Z, Mills T, Feng J, Liu CJ, Jing J, Cao J, Zhou B, Wang L, Zhou Y, Lin C, Guo AY, Chen X, Diao L, Li W, Chen Z, He X, Mills GB, Blackburn MR, Han L. Ruan H, et al. Among authors: chen z, chen x. Genome Med. 2019 Aug 26;11(1):55. doi: 10.1186/s13073-019-0663-5. Genome Med. 2019. PMID: 31446897 Free PMC article.
A microRNA 221- and 222-mediated feedback loop maintains constitutive activation of NFκB and STAT3 in colorectal cancer cells.
Liu S, Sun X, Wang M, Hou Y, Zhan Y, Jiang Y, Liu Z, Cao X, Chen P, Liu Z, Chen X, Tao Y, Xu C, Mao J, Cheng C, Li C, Hu Y, Wang L, Chin YE, Shi Y, Siebenlist U, Zhang X. Liu S, et al. Among authors: chen p, chen x. Gastroenterology. 2014 Oct;147(4):847-859.e11. doi: 10.1053/j.gastro.2014.06.006. Epub 2014 Jun 12. Gastroenterology. 2014. PMID: 24931456 Free PMC article.
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