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Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6.
Prins BP, Mead TJ, Brody JA, Sveinbjornsson G, Ntalla I, Bihlmeyer NA, van den Berg M, Bork-Jensen J, Cappellani S, Van Duijvenboden S, Klena NT, Gabriel GC, Liu X, Gulec C, Grarup N, Haessler J, Hall LM, Iorio A, Isaacs A, Li-Gao R, Lin H, Liu CT, Lyytikäinen LP, Marten J, Mei H, Müller-Nurasyid M, Orini M, Padmanabhan S, Radmanesh F, Ramirez J, Robino A, Schwartz M, van Setten J, Smith AV, Verweij N, Warren HR, Weiss S, Alonso A, Arnar DO, Bots ML, de Boer RA, Dominiczak AF, Eijgelsheim M, Ellinor PT, Guo X, Felix SB, Harris TB, Hayward C, Heckbert SR, Huang PL, Jukema JW, Kähönen M, Kors JA, Lambiase PD, Launer LJ, Li M, Linneberg A, Nelson CP, Pedersen O, Perez M, Peters A, Polasek O, Psaty BM, Raitakari OT, Rice KM, Rotter JI, Sinner MF, Soliman EZ, Spector TD, Strauch K, Thorsteinsdottir U, Tinker A, Trompet S, Uitterlinden A, Vaartjes I, van der Meer P, Völker U, Völzke H, Waldenberger M, Wilson JG, Xie Z, Asselbergs FW, Dörr M, van Duijn CM, Gasparini P, Gudbjartsson DF, Gudnason V, Hansen T, Kääb S, Kanters JK, Kooperberg C, Lehtimäki T, Lin HJ, Lubitz SA, Mook-Kanamori DO, Conti FJ, Newton-Cheh CH, Rosand J, Rudan I, Samani NJ, Sinagra G, Smith BH, Holm H, Stricke… See abstract for full author list ➔ Prins BP, et al. Among authors: isaacs a. Genome Biol. 2018 Jul 17;19(1):87. doi: 10.1186/s13059-018-1457-6. Genome Biol. 2018. PMID: 30012220 Free PMC article.
Haplotype analyses of the APOA5 gene in patients with familial combined hyperlipidemia.
van der Vleuten GM, Isaacs A, Zeng WW, ter Avest E, Talmud PJ, Dallinga-Thie GM, van Duijn CM, Stalenhoef AF, de Graaf J. van der Vleuten GM, et al. Among authors: isaacs a. Biochim Biophys Acta. 2007 Jan;1772(1):81-8. doi: 10.1016/j.bbadis.2006.10.012. Epub 2006 Oct 26. Biochim Biophys Acta. 2007. PMID: 17157483 Free article.
GenABEL: an R library for genome-wide association analysis.
Aulchenko YS, Ripke S, Isaacs A, van Duijn CM. Aulchenko YS, et al. Among authors: isaacs a. Bioinformatics. 2007 May 15;23(10):1294-6. doi: 10.1093/bioinformatics/btm108. Epub 2007 Mar 23. Bioinformatics. 2007. PMID: 17384015
The cholesteryl ester transfer protein I405V polymorphism is associated with increased high-density lipoprotein levels and decreased risk of myocardial infarction: the Rotterdam Study.
Isaacs A, Sayed-Tabatabaei FA, Hofman A, Oostra BA, Klungel OH, Maitland-Vander Zee AH, Stricker BH, Witteman JC, van Duijn CM. Isaacs A, et al. Eur J Cardiovasc Prev Rehabil. 2007 Jun;14(3):419-21. doi: 10.1097/HJR.0b013e32801101aa. Eur J Cardiovasc Prev Rehabil. 2007. PMID: 17568242
Eight-fold increased risk for congenital heart defects in children carrying the nicotinamide N-methyltransferase polymorphism and exposed to medicines and low nicotinamide.
van Driel LM, Smedts HP, Helbing WA, Isaacs A, Lindemans J, Uitterlinden AG, van Duijn CM, de Vries JH, Steegers EA, Steegers-Theunissen RP. van Driel LM, et al. Among authors: isaacs a. Eur Heart J. 2008 Jun;29(11):1424-31. doi: 10.1093/eurheartj/ehn170. Epub 2008 Apr 25. Eur Heart J. 2008. PMID: 18441319
709 results