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An enhanced CRISPR repressor for targeted mammalian gene regulation.
Yeo NC, Chavez A, Lance-Byrne A, Chan Y, Menn D, Milanova D, Kuo CC, Guo X, Sharma S, Tung A, Cecchi RJ, Tuttle M, Pradhan S, Lim ET, Davidsohn N, Ebrahimkhani MR, Collins JJ, Lewis NE, Kiani S, Church GM. Yeo NC, et al. Among authors: guo x. Nat Methods. 2018 Aug;15(8):611-616. doi: 10.1038/s41592-018-0048-5. Epub 2018 Jul 16. Nat Methods. 2018. PMID: 30013045 Free PMC article.
CRISPR Guide RNA Cloning for Mammalian Systems.
Nageshwaran S, Chavez A, Cher Yeo N, Guo X, Lance-Byrne A, Tung A, Collins JJ, Church GM. Nageshwaran S, et al. Among authors: guo x. J Vis Exp. 2018 Oct 2;(140):57998. doi: 10.3791/57998. J Vis Exp. 2018. PMID: 30346403 Free PMC article.
Accurate analysis of genuine CRISPR editing events with ampliCan.
Labun K, Guo X, Chavez A, Church G, Gagnon JA, Valen E. Labun K, et al. Among authors: guo x. Genome Res. 2019 May;29(5):843-847. doi: 10.1101/gr.244293.118. Epub 2019 Mar 8. Genome Res. 2019. PMID: 30850374 Free PMC article.
Orgo-Seq integrates single-cell and bulk transcriptomic data to identify cell type specific-driver genes associated with autism spectrum disorder.
Lim ET, Chan Y, Dawes P, Guo X, Erdin S, Tai DJC, Liu S, Reichert JM, Burns MJ, Chan YK, Chiang JJ, Meyer K, Zhang X, Walsh CA, Yankner BA, Raychaudhuri S, Hirschhorn JN, Gusella JF, Talkowski ME, Church GM. Lim ET, et al. Among authors: guo x. Nat Commun. 2022 Jun 10;13(1):3243. doi: 10.1038/s41467-022-30968-3. Nat Commun. 2022. PMID: 35688811 Free PMC article.
MegaGate: A toxin-less gateway molecular cloning tool.
Kramme C, Plesa AM, Wang HH, Wolf B, Smela MP, Guo X, Kohman RE, Chatterjee P, Church GM. Kramme C, et al. Among authors: guo x. STAR Protoc. 2021 Oct 22;2(4):100907. doi: 10.1016/j.xpro.2021.100907. eCollection 2021 Dec 17. STAR Protoc. 2021. PMID: 34746865 Free PMC article.
An integrated pipeline for mammalian genetic screening.
Kramme C, Plesa AM, Wang HH, Wolf B, Smela MP, Guo X, Kohman RE, Chatterjee P, Church GM. Kramme C, et al. Among authors: guo x. Cell Rep Methods. 2021 Sep 27;1(6):100082. doi: 10.1016/j.crmeth.2021.100082. eCollection 2021 Oct 25. Cell Rep Methods. 2021. PMID: 35474898 Free PMC article.
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