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Type 17-specific immune pathways are active in early spondyloarthritis.
Hughes CD, Ryan SE, Steel KJA, van den Beukel MD, Trouw LA, van Schie KAJ, Toes REM, Menon B, Kirkham BW, Taams LS. Hughes CD, et al. Among authors: van den beukel md. RMD Open. 2023 Dec 20;9(4):e003328. doi: 10.1136/rmdopen-2023-003328. RMD Open. 2023. PMID: 38123480 Free PMC article.
Antibodies against advanced glycation end-products and malondialdehyde-acetaldehyde adducts identify a new specific subgroup of hitherto patients with seronegative arthritis with a distinct clinical phenotype and an HLA class II association.
van den Beukel MD, van Wesemael TJ, Hoogslag ATW, Borggreven NV, Huizinga TW, van der Helm-van Mil AH, Toes RE, van der Woude D, Trouw LA. van den Beukel MD, et al. RMD Open. 2023 Dec 1;9(4):e003480. doi: 10.1136/rmdopen-2023-003480. RMD Open. 2023. PMID: 38053459 Free PMC article.
Commentary: Commentary: Antibodies against multiple post-translationally modified proteins aid in diagnosis of autoimmune hepatitis and associate with complete biochemical response to treatment.
van den Beukel MD, Stoelinga AEC, van der Meer AJ, van der Meulen S, Zhang L, Tushuizen ME, van Hoek B, Trouw LA. van den Beukel MD, et al. Front Med (Lausanne). 2023 Oct 23;10:1297191. doi: 10.3389/fmed.2023.1297191. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37937138 Free PMC article. No abstract available.
Antibodies against multiple post-translationally modified proteins aid in diagnosis of autoimmune hepatitis and associate with complete biochemical response to treatment.
van den Beukel MD, Stoelinga AEC, van der Meer AJ, van der Meulen S, Zhang L, Tushuizen ME, van Hoek B, Trouw LA. van den Beukel MD, et al. Front Med (Lausanne). 2023 Jul 25;10:1195747. doi: 10.3389/fmed.2023.1195747. eCollection 2023. Front Med (Lausanne). 2023. PMID: 37564051 Free PMC article.
Naturally produced type I IFNs enhance human myeloid dendritic cell maturation and IL-12p70 production and mediate elevated effector functions in innate and adaptive immune cells.
Sköld AE, Mathan TSM, van Beek JJP, Flórez-Grau G, van den Beukel MD, Sittig SP, Wimmers F, Bakdash G, Schreibelt G, de Vries IJM. Sköld AE, et al. Among authors: van den beukel md. Cancer Immunol Immunother. 2018 Sep;67(9):1425-1436. doi: 10.1007/s00262-018-2204-2. Epub 2018 Jul 13. Cancer Immunol Immunother. 2018. PMID: 30019146 Free PMC article.