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Combination Therapies Using Metformin and/or Valproic Acid in Prostate Cancer: Possible Mechanistic Interactions.
Curr Cancer Drug Targets. 2019;19(5):368-381. doi: 10.2174/1568009618666180724111604.
Curr Cancer Drug Targets. 2019.
PMID: 30039761
Review.
The Combination of Metformin and Valproic Acid Induces Synergistic Apoptosis in the Presence of p53 and Androgen Signaling in Prostate Cancer.
Tran LNK, Kichenadasse G, Butler LM, Centenera MM, Morel KL, Ormsby RJ, Michael MZ, Lower KM, Sykes PJ.
Tran LNK, et al.
Mol Cancer Ther. 2017 Dec;16(12):2689-2700. doi: 10.1158/1535-7163.MCT-17-0074. Epub 2017 Aug 11.
Mol Cancer Ther. 2017.
PMID: 28802253
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The Combination of Metformin and Valproic Acid Has a Greater Anti-tumoral Effect on Prostate Cancer Growth In Vivo than Either Drug Alone.
Tran LNK, Kichenadasse G, Morel KL, Lavranos TC, Klebe S, Lower KM, Ormsby RJ, Elliot DJ, Sykes PJ.
Tran LNK, et al.
In Vivo. 2019 Jan-Feb;33(1):99-108. doi: 10.21873/invivo.11445.
In Vivo. 2019.
PMID: 30587609
Free PMC article.
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Chronic low dose ethanol induces an aggressive metastatic phenotype in TRAMP mice, which is counteracted by parthenolide.
Morel KL, Ormsby RJ, Solly EL, Tran LNK, Sweeney CJ, Klebe S, Cordes N, Sykes PJ.
Morel KL, et al. Among authors: tran lnk.
Clin Exp Metastasis. 2018 Oct;35(7):649-661. doi: 10.1007/s10585-018-9915-9. Epub 2018 Jun 23.
Clin Exp Metastasis. 2018.
PMID: 29936575
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