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Page 1
Type 2 diabetes risk alleles in PAM impact insulin release from human pancreatic β-cells.
Thomsen SK, Raimondo A, Hastoy B, Sengupta S, Dai XQ, Bautista A, Censin J, Payne AJ, Umapathysivam MM, Spigelman AF, Barrett A, Groves CJ, Beer NL, Manning Fox JE, McCarthy MI, Clark A, Mahajan A, Rorsman P, MacDonald PE, Gloyn AL. Thomsen SK, et al. Among authors: hastoy b. Nat Genet. 2018 Aug;50(8):1122-1131. doi: 10.1038/s41588-018-0173-1. Epub 2018 Jul 27. Nat Genet. 2018. PMID: 30054598 Free PMC article.
MicroRNA-7a regulates pancreatic β cell function.
Latreille M, Hausser J, Stützer I, Zhang Q, Hastoy B, Gargani S, Kerr-Conte J, Pattou F, Zavolan M, Esguerra JL, Eliasson L, Rülicke T, Rorsman P, Stoffel M. Latreille M, et al. Among authors: hastoy b. J Clin Invest. 2014 Jun;124(6):2722-35. doi: 10.1172/JCI73066. Epub 2014 May 1. J Clin Invest. 2014. PMID: 24789908 Free PMC article.
Glutamate acts as a key signal linking glucose metabolism to incretin/cAMP action to amplify insulin secretion.
Gheni G, Ogura M, Iwasaki M, Yokoi N, Minami K, Nakayama Y, Harada K, Hastoy B, Wu X, Takahashi H, Kimura K, Matsubara T, Hoshikawa R, Hatano N, Sugawara K, Shibasaki T, Inagaki N, Bamba T, Mizoguchi A, Fukusaki E, Rorsman P, Seino S. Gheni G, et al. Among authors: hastoy b. Cell Rep. 2014 Oct 23;9(2):661-73. doi: 10.1016/j.celrep.2014.09.030. Epub 2014 Oct 16. Cell Rep. 2014. PMID: 25373904 Free PMC article.
RFX6 regulates insulin secretion by modulating Ca2+ homeostasis in human β cells.
Chandra V, Albagli-Curiel O, Hastoy B, Piccand J, Randriamampita C, Vaillant E, Cavé H, Busiah K, Froguel P, Vaxillaire M, Rorsman P, Polak M, Scharfmann R. Chandra V, et al. Among authors: hastoy b. Cell Rep. 2014 Dec 24;9(6):2206-18. doi: 10.1016/j.celrep.2014.11.010. Epub 2014 Dec 11. Cell Rep. 2014. PMID: 25497100 Free article.
The β-cell assassin: IAPP cytotoxicity.
Raleigh D, Zhang X, Hastoy B, Clark A. Raleigh D, et al. Among authors: hastoy b. J Mol Endocrinol. 2017 Oct;59(3):R121-R140. doi: 10.1530/JME-17-0105. Epub 2017 Aug 15. J Mol Endocrinol. 2017. PMID: 28811318 Review.
NKX6.1 induced pluripotent stem cell reporter lines for isolation and analysis of functionally relevant neuronal and pancreas populations.
Gupta SK, Wesolowska-Andersen A, Ringgaard AK, Jaiswal H, Song L, Hastoy B, Ingvorsen C, Taheri-Ghahfarokhi A, Magnusson B, Maresca M, Jensen RR, Beer NL, Fels JJ, Grunnet LG, Thomas MK, Gloyn AL, Hicks R, McCarthy MI, Hansson M, Honoré C. Gupta SK, et al. Among authors: hastoy b. Stem Cell Res. 2018 May;29:220-231. doi: 10.1016/j.scr.2018.04.010. Epub 2018 Apr 23. Stem Cell Res. 2018. PMID: 29734117 Free article.
Insulin inhibits glucagon release by SGLT2-induced stimulation of somatostatin secretion.
Vergari E, Knudsen JG, Ramracheya R, Salehi A, Zhang Q, Adam J, Asterholm IW, Benrick A, Briant LJB, Chibalina MV, Gribble FM, Hamilton A, Hastoy B, Reimann F, Rorsman NJG, Spiliotis II, Tarasov A, Wu Y, Ashcroft FM, Rorsman P. Vergari E, et al. Among authors: hastoy b. Nat Commun. 2019 Jan 11;10(1):139. doi: 10.1038/s41467-018-08193-8. Nat Commun. 2019. PMID: 30635569 Free PMC article.
24 results