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Comprehensive Analysis of Alternative Splicing Across Tumors from 8,705 Patients.
Kahles A, Lehmann KV, Toussaint NC, Hüser M, Stark SG, Sachsenberg T, Stegle O, Kohlbacher O, Sander C; Cancer Genome Atlas Research Network; Rätsch G. Kahles A, et al. Among authors: toussaint nc. Cancer Cell. 2018 Aug 13;34(2):211-224.e6. doi: 10.1016/j.ccell.2018.07.001. Epub 2018 Aug 2. Cancer Cell. 2018. PMID: 30078747 Free PMC article.
Exploiting physico-chemical properties in string kernels.
Toussaint NC, Widmer C, Kohlbacher O, Rätsch G. Toussaint NC, et al. BMC Bioinformatics. 2010 Oct 26;11 Suppl 8(Suppl 8):S7. doi: 10.1186/1471-2105-11-S8-S7. BMC Bioinformatics. 2010. PMID: 21034432 Free PMC article.
Binding pocket optimization by computational protein design.
Malisi C, Schumann M, Toussaint NC, Kageyama J, Kohlbacher O, Höcker B. Malisi C, et al. Among authors: toussaint nc. PLoS One. 2012;7(12):e52505. doi: 10.1371/journal.pone.0052505. Epub 2012 Dec 27. PLoS One. 2012. PMID: 23300688 Free PMC article.
Towards in silico design of epitope-based vaccines.
Toussaint NC, Kohlbacher O. Toussaint NC, et al. Expert Opin Drug Discov. 2009 Oct;4(10):1047-60. doi: 10.1517/17460440903242283. Epub 2009 Aug 28. Expert Opin Drug Discov. 2009. PMID: 23480396
In melanoma, Hippo signaling is affected by copy number alterations and YAP1 overexpression impairs patient survival.
Menzel M, Meckbach D, Weide B, Toussaint NC, Schilbach K, Noor S, Eigentler T, Ikenberg K, Busch C, Quintanilla-Martinez L, Kohlhofer U, Göke A, Göke F, Handgretinger R, Ottmann C, Bastian BC, Garbe C, Röcken M, Perner S, Kohlbacher O, Bauer J. Menzel M, et al. Among authors: toussaint nc. Pigment Cell Melanoma Res. 2014 Jul;27(4):671-3. doi: 10.1111/pcmr.12249. Epub 2014 May 6. Pigment Cell Melanoma Res. 2014. PMID: 24703331 No abstract available.
44 results