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Inhibition of the Stromal p38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone Loss.
Murali B, Ren Q, Luo X, Faget DV, Wang C, Johnson RM, Gruosso T, Flanagan KC, Fu Y, Leahy K, Alspach E, Su X, Ross MH, Burnette B, Weilbaecher KN, Park M, Mbalaviele G, Monahan JB, Stewart SA. Murali B, et al. Among authors: stewart sa. Cancer Res. 2018 Oct 1;78(19):5618-5630. doi: 10.1158/0008-5472.CAN-18-0234. Epub 2018 Aug 9. Cancer Res. 2018. PMID: 30093561 Free PMC article.
Senescent stromal-derived osteopontin promotes preneoplastic cell growth.
Pazolli E, Luo X, Brehm S, Carbery K, Chung JJ, Prior JL, Doherty J, Demehri S, Salavaggione L, Piwnica-Worms D, Stewart SA. Pazolli E, et al. Among authors: stewart sa. Cancer Res. 2009 Feb 1;69(3):1230-9. doi: 10.1158/0008-5472.CAN-08-2970. Epub 2009 Jan 20. Cancer Res. 2009. PMID: 19155301 Free PMC article.
Senescence and the pro-tumorigenic stroma.
Alspach E, Fu Y, Stewart SA. Alspach E, et al. Among authors: stewart sa. Crit Rev Oncog. 2013;18(6):549-58. doi: 10.1615/critrevoncog.2014010630. Crit Rev Oncog. 2013. PMID: 24579734 Free PMC article. Review.
p38MAPK plays a crucial role in stromal-mediated tumorigenesis.
Alspach E, Flanagan KC, Luo X, Ruhland MK, Huang H, Pazolli E, Donlin MJ, Marsh T, Piwnica-Worms D, Monahan J, Novack DV, McAllister SS, Stewart SA. Alspach E, et al. Among authors: stewart sa. Cancer Discov. 2014 Jun;4(6):716-29. doi: 10.1158/2159-8290.CD-13-0743. Epub 2014 Mar 26. Cancer Discov. 2014. PMID: 24670723 Free PMC article.
Flap Endonuclease 1 Limits Telomere Fragility on the Leading Strand.
Teasley DC, Parajuli S, Nguyen M, Moore HR, Alspach E, Lock YJ, Honaker Y, Saharia A, Piwnica-Worms H, Stewart SA. Teasley DC, et al. Among authors: stewart sa. J Biol Chem. 2015 Jun 12;290(24):15133-45. doi: 10.1074/jbc.M115.647388. Epub 2015 Apr 28. J Biol Chem. 2015. PMID: 25922071 Free PMC article.
Stromal-Initiated Changes in the Bone Promote Metastatic Niche Development.
Luo X, Fu Y, Loza AJ, Murali B, Leahy KM, Ruhland MK, Gang M, Su X, Zamani A, Shi Y, Lavine KJ, Ornitz DM, Weilbaecher KN, Long F, Novack DV, Faccio R, Longmore GD, Stewart SA. Luo X, et al. Among authors: stewart sa. Cell Rep. 2016 Jan 5;14(1):82-92. doi: 10.1016/j.celrep.2015.12.016. Epub 2015 Dec 24. Cell Rep. 2016. PMID: 26725121 Free PMC article.
205 results