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Single-cell transcriptomes from human kidneys reveal the cellular identity of renal tumors.
Young MD, Mitchell TJ, Vieira Braga FA, Tran MGB, Stewart BJ, Ferdinand JR, Collord G, Botting RA, Popescu DM, Loudon KW, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Del Castillo Velasco-Herrera M, Guzzo C, Richoz N, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Maxwell PH, Lindsay S, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Clatworthy M, Behjati S. Young MD, et al. Among authors: coleman n. Science. 2018 Aug 10;361(6402):594-599. doi: 10.1126/science.aat1699. Science. 2018. PMID: 30093597 Free PMC article.
Pediatric malignant germ cell tumors show characteristic transcriptome profiles.
Palmer RD, Barbosa-Morais NL, Gooding EL, Muralidhar B, Thornton CM, Pett MR, Roberts I, Schneider DT, Thorne N, Tavaré S, Nicholson JC, Coleman N; Children's Cancer and Leukaemia Group. Palmer RD, et al. Among authors: coleman n. Cancer Res. 2008 Jun 1;68(11):4239-47. doi: 10.1158/0008-5472.CAN-07-5560. Cancer Res. 2008. PMID: 18519683
Malignant germ cell tumors display common microRNA profiles resulting in global changes in expression of messenger RNA targets.
Palmer RD, Murray MJ, Saini HK, van Dongen S, Abreu-Goodger C, Muralidhar B, Pett MR, Thornton CM, Nicholson JC, Enright AJ, Coleman N; Children's Cancer and Leukaemia Group. Palmer RD, et al. Among authors: coleman n. Cancer Res. 2010 Apr 1;70(7):2911-23. doi: 10.1158/0008-5472.CAN-09-3301. Epub 2010 Mar 23. Cancer Res. 2010. PMID: 20332240 Free PMC article.
The two most common histological subtypes of malignant germ cell tumour are distinguished by global microRNA profiles, associated with differential transcription factor expression.
Murray MJ, Saini HK, van Dongen S, Palmer RD, Muralidhar B, Pett MR, Piipari M, Thornton CM, Nicholson JC, Enright AJ, Coleman N. Murray MJ, et al. Among authors: coleman n. Mol Cancer. 2010 Nov 8;9:290. doi: 10.1186/1476-4598-9-290. Mol Cancer. 2010. PMID: 21059207 Free PMC article.
Solid tumors of childhood display specific serum microRNA profiles.
Murray MJ, Raby KL, Saini HK, Bailey S, Wool SV, Tunnacliffe JM, Enright AJ, Nicholson JC, Coleman N. Murray MJ, et al. Among authors: coleman n. Cancer Epidemiol Biomarkers Prev. 2015 Feb;24(2):350-60. doi: 10.1158/1055-9965.EPI-14-0669. Epub 2014 Nov 21. Cancer Epidemiol Biomarkers Prev. 2015. PMID: 25416717 Free PMC article. Clinical Trial.
Paediatric extracranial germ-cell tumours.
Shaikh F, Murray MJ, Amatruda JF, Coleman N, Nicholson JC, Hale JP, Pashankar F, Stoneham SJ, Poynter JN, Olson TA, Billmire DF, Stark D, Rodriguez-Galindo C, Frazier AL. Shaikh F, et al. Among authors: coleman n. Lancet Oncol. 2016 Apr;17(4):e149-e162. doi: 10.1016/S1470-2045(15)00545-8. Epub 2016 Mar 29. Lancet Oncol. 2016. PMID: 27300675 Free article. Review.
Spatiotemporal immune zonation of the human kidney.
Stewart BJ, Ferdinand JR, Young MD, Mitchell TJ, Loudon KW, Riding AM, Richoz N, Frazer GL, Staniforth JUL, Vieira Braga FA, Botting RA, Popescu DM, Vento-Tormo R, Stephenson E, Cagan A, Farndon SJ, Polanski K, Efremova M, Green K, Del Castillo Velasco-Herrera M, Guzzo C, Collord G, Mamanova L, Aho T, Armitage JN, Riddick ACP, Mushtaq I, Farrell S, Rampling D, Nicholson J, Filby A, Burge J, Lisgo S, Lindsay S, Bajenoff M, Warren AY, Stewart GD, Sebire N, Coleman N, Haniffa M, Teichmann SA, Behjati S, Clatworthy MR. Stewart BJ, et al. Among authors: coleman n. Science. 2019 Sep 27;365(6460):1461-1466. doi: 10.1126/science.aat5031. Science. 2019. PMID: 31604275 Free PMC article.
Embryonal precursors of Wilms tumor.
Coorens THH, Treger TD, Al-Saadi R, Moore L, Tran MGB, Mitchell TJ, Tugnait S, Thevanesan C, Young MD, Oliver TRW, Oostveen M, Collord G, Tarpey PS, Cagan A, Hooks Y, Brougham M, Reynolds BC, Barone G, Anderson J, Jorgensen M, Burke GAA, Visser J, Nicholson JC, Smeulders N, Mushtaq I, Stewart GD, Campbell PJ, Wedge DC, Martincorena I, Rampling D, Hook L, Warren AY, Coleman N, Chowdhury T, Sebire N, Drost J, Saeb-Parsy K, Stratton MR, Straathof K, Pritchard-Jones K, Behjati S. Coorens THH, et al. Among authors: coleman n. Science. 2019 Dec 6;366(6470):1247-1251. doi: 10.1126/science.aax1323. Science. 2019. PMID: 31806814 Free PMC article.
650 results