Guptaroy B - Search Results

1

Tamoxifen Directly Interacts with the Dopamine Transporter.

Mikelman SR, Guptaroy B, Schmitt KC, Jones KT, Zhen J, Reith MEA, Gnegy ME. Mikelman SR, et al. Among authors: guptaroy b. J Pharmacol Exp Ther. 2018 Oct;367(1):119-128. doi: 10.1124/jpet.118.248179. Epub 2018 Aug 14. J Pharmacol Exp Ther. 2018. PMID: 30108161 Free PMC article.

2

Repeated amphetamine couples norepinephrine transporter and calcium channel activities in PC12 cells.

Kantor L, Zhang M, Guptaroy B, Park YH, Gnegy ME. Kantor L, et al. Among authors: guptaroy b. J Pharmacol Exp Ther. 2004 Dec;311(3):1044-51. doi: 10.1124/jpet.104.071068. Epub 2004 Aug 30. J Pharmacol Exp Ther. 2004. PMID: 15340003

3

Rapid delivery of the dopamine transporter to the plasmalemmal membrane upon amphetamine stimulation.

Johnson LA, Furman CA, Zhang M, Guptaroy B, Gnegy ME. Johnson LA, et al. Among authors: guptaroy b. Neuropharmacology. 2005 Nov;49(6):750-8. doi: 10.1016/j.neuropharm.2005.08.018. Epub 2005 Oct 5. Neuropharmacology. 2005. PMID: 16212991

4

Simple transporter trafficking model for amphetamine-induced dopamine efflux.

Thwar PK, Guptaroy B, Zhang M, Gnegy ME, Burns MA, Linderman JJ. Thwar PK, et al. Among authors: guptaroy b. Synapse. 2007 Jul;61(7):500-14. doi: 10.1002/syn.20390. Synapse. 2007. PMID: 17415796 Free article.

5

A juxtamembrane mutation in the N terminus of the dopamine transporter induces preference for an inward-facing conformation.

Guptaroy B, Zhang M, Bowton E, Binda F, Shi L, Weinstein H, Galli A, Javitch JA, Neubig RR, Gnegy ME. Guptaroy B, et al. Mol Pharmacol. 2009 Mar;75(3):514-24. doi: 10.1124/mol.108.048744. Epub 2008 Dec 19. Mol Pharmacol. 2009. PMID: 19098122 Free PMC article.

6

Dopamine and amphetamine rapidly increase dopamine transporter trafficking to the surface: live-cell imaging using total internal reflection fluorescence microscopy.

Furman CA, Chen R, Guptaroy B, Zhang M, Holz RW, Gnegy M. Furman CA, et al. Among authors: guptaroy b. J Neurosci. 2009 Mar 11;29(10):3328-36. doi: 10.1523/JNEUROSCI.5386-08.2009. J Neurosci. 2009. PMID: 19279270 Free PMC article.

7

Site-directed mutations near transmembrane domain 1 alter conformation and function of norepinephrine and dopamine transporters.

Guptaroy B, Fraser R, Desai A, Zhang M, Gnegy ME. Guptaroy B, et al. Mol Pharmacol. 2011 Mar;79(3):520-32. doi: 10.1124/mol.110.069039. Epub 2010 Dec 13. Mol Pharmacol. 2011. PMID: 21149640 Free PMC article.

8

An N-terminal threonine mutation produces an efflux-favorable, sodium-primed conformation of the human dopamine transporter.

Fraser R, Chen Y, Guptaroy B, Luderman KD, Stokes SL, Beg A, DeFelice LJ, Gnegy ME. Fraser R, et al. Among authors: guptaroy b. Mol Pharmacol. 2014 Jul;86(1):76-85. doi: 10.1124/mol.114.091926. Epub 2014 Apr 21. Mol Pharmacol. 2014. PMID: 24753048 Free PMC article.

9

Tamoxifen and its active metabolites inhibit dopamine transporter function independently of the estrogen receptors.

Mikelman SR, Guptaroy B, Gnegy ME. Mikelman SR, et al. Among authors: guptaroy b. J Neurochem. 2017 Apr;141(1):31-36. doi: 10.1111/jnc.13955. Epub 2017 Feb 14. J Neurochem. 2017. PMID: 28075498 Free article.

10

Direct and Systemic Administration of a CNS-Permeant Tamoxifen Analog Reduces Amphetamine-Induced Dopamine Release and Reinforcing Effects.

Carpenter C, Zestos AG, Altshuler R, Sorenson RJ, Guptaroy B, Showalter HD, Kennedy RT, Jutkiewicz E, Gnegy ME. Carpenter C, et al. Among authors: guptaroy b. Neuropsychopharmacology. 2017 Sep;42(10):1940-1949. doi: 10.1038/npp.2017.95. Epub 2017 May 11. Neuropsychopharmacology. 2017. PMID: 28492278 Free PMC article.

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