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Genome-wide mapping of plasma protein QTLs identifies putatively causal genes and pathways for cardiovascular disease.
Yao C, Chen G, Song C, Keefe J, Mendelson M, Huan T, Sun BB, Laser A, Maranville JC, Wu H, Ho JE, Courchesne P, Lyass A, Larson MG, Gieger C, Graumann J, Johnson AD, Danesh J, Runz H, Hwang SJ, Liu C, Butterworth AS, Suhre K, Levy D. Yao C, et al. Among authors: courchesne p. Nat Commun. 2018 Aug 15;9(1):3268. doi: 10.1038/s41467-018-05512-x. Nat Commun. 2018. PMID: 30111768 Free PMC article.
A systems biology framework identifies molecular underpinnings of coronary heart disease.
Huan T, Zhang B, Wang Z, Joehanes R, Zhu J, Johnson AD, Ying S, Munson PJ, Raghavachari N, Wang R, Liu P, Courchesne P, Hwang SJ, Assimes TL, McPherson R, Samani NJ, Schunkert H; Coronary ARteryDIsease Genome wide Replication and Meta-analysis (CARDIoGRAM) Consortium, International Consortium for Blood Pressure GWAS (ICBP); Meng Q, Suver C, O'Donnell CJ, Derry J, Yang X, Levy D. Huan T, et al. Among authors: courchesne p. Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1427-34. doi: 10.1161/ATVBAHA.112.300112. Epub 2013 Mar 28. Arterioscler Thromb Vasc Biol. 2013. PMID: 23539213 Free PMC article.
Gene expression signatures of coronary heart disease.
Joehanes R, Ying S, Huan T, Johnson AD, Raghavachari N, Wang R, Liu P, Woodhouse KA, Sen SK, Tanriverdi K, Courchesne P, Freedman JE, O'Donnell CJ, Levy D, Munson PJ. Joehanes R, et al. Among authors: courchesne p. Arterioscler Thromb Vasc Biol. 2013 Jun;33(6):1418-26. doi: 10.1161/ATVBAHA.112.301169. Epub 2013 Mar 28. Arterioscler Thromb Vasc Biol. 2013. PMID: 23539218 Free PMC article.
Protein biomarkers of new-onset cardiovascular disease: prospective study from the systems approach to biomarker research in cardiovascular disease initiative.
Yin X, Subramanian S, Hwang SJ, O'Donnell CJ, Fox CS, Courchesne P, Muntendam P, Gordon N, Adourian A, Juhasz P, Larson MG, Levy D. Yin X, et al. Among authors: courchesne p. Arterioscler Thromb Vasc Biol. 2014 Apr;34(4):939-45. doi: 10.1161/ATVBAHA.113.302918. Epub 2014 Feb 13. Arterioscler Thromb Vasc Biol. 2014. PMID: 24526693 Free PMC article.
Stromal cell-derived factor 1 as a biomarker of heart failure and mortality risk.
Subramanian S, Liu C, Aviv A, Ho JE, Courchesne P, Muntendam P, Larson MG, Cheng S, Wang TJ, Mehta NN, Levy D. Subramanian S, et al. Among authors: courchesne p. Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):2100-5. doi: 10.1161/ATVBAHA.114.303579. Epub 2014 Jul 24. Arterioscler Thromb Vasc Biol. 2014. PMID: 25060794 Free PMC article.
Integromic analysis of genetic variation and gene expression identifies networks for cardiovascular disease phenotypes.
Yao C, Chen BH, Joehanes R, Otlu B, Zhang X, Liu C, Huan T, Tastan O, Cupples LA, Meigs JB, Fox CS, Freedman JE, Courchesne P, O'Donnell CJ, Munson PJ, Keles S, Levy D. Yao C, et al. Among authors: courchesne p. Circulation. 2015 Feb 10;131(6):536-49. doi: 10.1161/CIRCULATIONAHA.114.010696. Epub 2014 Dec 22. Circulation. 2015. PMID: 25533967 Free PMC article.
A systematic heritability analysis of the human whole blood transcriptome.
Huan T, Liu C, Joehanes R, Zhang X, Chen BH, Johnson AD, Yao C, Courchesne P, O'Donnell CJ, Munson PJ, Levy D. Huan T, et al. Among authors: courchesne p. Hum Genet. 2015 Mar;134(3):343-58. doi: 10.1007/s00439-014-1524-3. Epub 2015 Jan 14. Hum Genet. 2015. PMID: 25585846 Free PMC article.
Dissecting the roles of microRNAs in coronary heart disease via integrative genomic analyses.
Huan T, Rong J, Tanriverdi K, Meng Q, Bhattacharya A, McManus DD, Joehanes R, Assimes TL, McPherson R, Samani NJ, Erdmann J, Schunkert H, Courchesne P, Munson PJ, Johnson AD, O'Donnell CJ, Zhang B, Larson MG, Freedman JE, Levy D, Yang X. Huan T, et al. Among authors: courchesne p. Arterioscler Thromb Vasc Biol. 2015 Apr;35(4):1011-21. doi: 10.1161/ATVBAHA.114.305176. Epub 2015 Feb 5. Arterioscler Thromb Vasc Biol. 2015. PMID: 25657313 Free PMC article.
A meta-analysis of gene expression signatures of blood pressure and hypertension.
Huan T, Esko T, Peters MJ, Pilling LC, Schramm K, Schurmann C, Chen BH, Liu C, Joehanes R, Johnson AD, Yao C, Ying SX, Courchesne P, Milani L, Raghavachari N, Wang R, Liu P, Reinmaa E, Dehghan A, Hofman A, Uitterlinden AG, Hernandez DG, Bandinelli S, Singleton A, Melzer D, Metspalu A, Carstensen M, Grallert H, Herder C, Meitinger T, Peters A, Roden M, Waldenberger M, Dörr M, Felix SB, Zeller T; International Consortium for Blood Pressure GWAS (ICBP); Vasan R, O'Donnell CJ, Munson PJ, Yang X, Prokisch H, Völker U, van Meurs JB, Ferrucci L, Levy D. Huan T, et al. Among authors: courchesne p. PLoS Genet. 2015 Mar 18;11(3):e1005035. doi: 10.1371/journal.pgen.1005035. eCollection 2015 Mar. PLoS Genet. 2015. PMID: 25785607 Free PMC article.
48 results